Estimated vaccine effectiveness against SARS-CoV-2 Delta and Omicron infections among health care workers and the general adult population in Norway, August 2021 – January 2022

Langlete, Petter; Tesli, Martin; Veneti, Lamprini; Starrfelt, Jostein; Elstrøm, Petter; Meijerink, Hinta

doi:10.1016/j.vaccine.2023.05.022

Cited by 5 publications

(1 citation statement)

References 22 publications

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“…It was shown that this effectiveness was higher for the Delta variant than for the Omicron variant in both HCWs and non-HCWs. Surprisingly, vaccine effectiveness was higher among HCWs during the Omicron wave, perhaps linked to better prevention measures and routine testing [24]. A decrease in humoral response 6 months after the second dose of BNT162b2 was clearly demonstrated among vaccinated Israeli HCWs: the level of IgG antibodies decreased at a constant rate, whereas the neutralizing antibody level decreased rapidly for the first three months, with a slower decrease thereafter.…”

Section: Discussionmentioning

confidence: 98%

COVID-19 Infection despite Previous Vaccination in Cancer Patients and Healthcare Workers: Results from a French Prospective Multicenter Cohort (PAPESCO-19)

Seegers,

Rousseau,

Zhou

et al. 2023

Cancers

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In a multicenter prospective cohort of cancer patients (CP; n = 840) and healthcare workers (HCWs; n = 935) vaccinated against COVID-19, we noticed the following: i/after vaccination, 4.4% of HCWs and 5.8% of CP were infected; ii/no characteristic was associated with post-vaccine COVID-19 infections among HCWs; iii/CP who developed infections were younger, more frequently women (NS), more frequently had gastrointestinal, gynecological, or breast cancer and a localized cancer stage; iv/CP vaccinated while receiving chemotherapy or targeted therapy had (NS) more breakthrough infections after vaccination than those vaccinated after these treatments; the opposite was noted with radiotherapy, immunotherapy, or hormonotherapy; v/most COVID-19 infections occurred either during the Alpha wave (11/41 HCW, 20/49 CP), early after the first vaccination campaign started, or during the Omicron wave (21/41 HCW, 20/49 CP), more than 3 months after the second dose; vi/risk of infection was not associated with values of antibody titers; vii/the outcome of these COVID-19 infections after vaccination was not severe in all cases. To conclude, around 5% of our CPs or HCWs developed a COVID-19 infection despite previous vaccination. The outcome of these infections was not severe.

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Section: Discussionmentioning

confidence: 98%