ABSTRACT.
When choosing a design for estimating product differences we must consider both the appropriate model for the analysis of results and the economic aspects of the test. If no residual effects are expected the SMD design provides an efficient way of estimating the product difference. If the residual effect is known to be present it is better to consider an alternative design. The choice of an alternative will depend on both theoretical (desired precision of estimates) and practical (cost of conducting a study) considerations. In this paper, I review both the theoretical underpinnings of SMD and some of its possible alternatives.