Estimates of the Number of People Living with HIV in Italy

Camoni, Laura; Règine, Vincenza; Stanecki, Karen; Salfa, Maria Cristina; Raimondo, Mariangela; Suligoi, Barbara

doi:10.1155/2014/209619

Cited by 21 publications

(21 citation statements)

References 13 publications

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“…The estimated number of PLHIV of about 114,812-156,910 is similar to the estimate (110,000-140,000) ob-tained for Italy in 2012 using the EPP/Spectrum package of the UNAIDS 23,24 : this package incorporates surveillance data, results of prevalence surveys, and national demographic data in a mathematical model that generates estimates of prevalent cases and incidence trends over time. It must be stressed that in the HIV care continuum the estimated number of PLHIV depends on the proportion of people undiagnosed or not linked to care.…”

Section: Discussionsupporting

confidence: 63%

Estimating Minimum Adult HIV Prevalence: A Cross-Sectional Study to Assess the Characteristics of People Living with HIV in Italy

Camoni¹,

Raimondo²,

Dorrucci³

et al. 2015

AIDS Research and Human Retroviruses

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In 2012, we conducted a retrospective cross-sectional study to assess the number of people living with HIV linked to care and, among these, the number of people on antiretroviral therapy. The health authority in each of the 20 Italian Regions provided the list of Public Infectious Diseases Clinics providing antiretroviral therapy and monitoring people with HIV infection. We asked every Public Infectious Diseases Clinic to report the number of HIV-positive people diagnosed and linked to care and the number of those on antiretroviral therapy during 2012. In 2012, 94,146 people diagnosed with HIV and linked to care were reported. The majority were males (70.1%), Italians (84.4%), and aged between 25 and 49 years (63.4%); the probable route of transmission was heterosexual contact in 37.5% of cases, injecting drug use in 28.1%, and male-to-male contact in 27.9%. Among people in care, 20.1% had less than 350 CD4 cells/μl, 87.6% received antiretroviral therapy, and among these, 62.4% had a CD4 cell count higher than 350 cells/μl. The overall estimated prevalence of individuals diagnosed and linked to care in 2012 in Italy was 0.16 per 100 residents (all ages). Adding the estimated proportion of undiagnosed people, the estimated HIV prevalence would range between 0.19 and 0.26 per 100 residents. In Italy, the majority of people diagnosed and linked to care receive antiretroviral therapy. A higher prevalence of individuals diagnosed and linked to care was observed in Northern Italy and among males. More information for developing the HIV care continuum is necessary to improve the entire engagement in care, focusing on test-and-treat strategies to substantially reduce the proportion of people still undiagnosed or with a detectable viral load.

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Section: Discussionsupporting

confidence: 63%

Estimating Minimum Adult HIV Prevalence: A Cross-Sectional Study to Assess the Characteristics of People Living with HIV in Italy

Camoni¹,

Raimondo²,

Dorrucci³

et al. 2015

AIDS Research and Human Retroviruses

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“…Italy, with about 60 million of inhabitants (201 inhabitants per square kilometer) and about four thousand new diagnoses of HIV infection annually, contributes significantly to outline the profile of the HIV epidemic in EU. A total of 123000 (115000–145000) individuals aged 15 or more were estimated to be living with HIV/AIDS in Italy at the end of 2012 . The estimated HIV prevalence among adults in Italy in 2012 was 0.28 (0.24–0.32) per 100 residents aged 15 or more.…”

Section: Discussionmentioning

confidence: 99%

Organ transplantation from “increased infectious risk donors”: the experience of the Nord Italia Transplant program - A retrospective study

et al. 2017

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The purpose of this study was to assess the safety and the clinical outcome associated with organ transplantation from increased infectious risk donors (IRD). We retrospectively identified all adult deceased IRD referred to the Nord Italia Transplant program coordinating center from November 2006 to November 2011. All potential donors were screened for social risk factors that may increase the risk of donor-derived infection with human immunodeficiency (HIV), hepatitis B virus (HBV), or hepatitis C virus (HCV). All recipients were followed monthly for the first 6 months post-transplant. A total of 86 potential IRD were identified during the study period. Three hundred and seventy-nine organs from IRD were offered to the transplant centers, but only 185 (48.8%) were used for transplantation. Organs from IRD were transplanted into 174 recipients. The complete follow-up data were available for 152 of 174 (87.3%) recipients. During a mean follow-up of 11.7 months (median 12; range 2.4-12), no transmission of HIV, HBV, or syphilis was documented by serology and nucleic acid testing (NAT) testing. Two patients transplanted with organs from HCV-RNA-positive donors, as expected, developed post-transplant HCV infection. In conclusion, the use of organs from IRD was associated with a safe increase in the transplant procedures in our country.

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“…In Italia, ad oggi, sono state stimate circa 123.000 (115.000-145.000) persone che vivono con l'infezione da HIV-1 (6). Il costo per singolo paziente ammonta a circa 10,000€ l'anno.…”

Section: Costi Dell'hivunclassified

La conta dei linfociti nel monitoraggio del paziente con infezione da HIV: evidenze per un impiego ragionato

Biagio¹,

Sirello²,

Riccardi³

2016

JHA

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Riassunto La conta dei linfociti CD4+ è un esame essenziale per stabilire il grado di immunodepressione dei pazienti con infezione da HIV. Inoltre ci fornisce la stima del recupero immunitario e recentemente il suo ruolo ha acquisito importanza con la valutazione del rapporto CD4/CD8. Recenti studi clinici hanno però dimostrato come la conta dei linfociti CD4 possa essere non sempre necessaria nei pazienti stabili. Questo articolo approfondisce la letteratura scientifica a supporto dell'ipotesi di aumentare l'intervallo tra una determinazione e l'altra dei CD4, nei pazienti con infezione da HIV, e le possibili conseguenze sulla spesa del servizio sanitario nazionale.

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Estimates of the Number of People Living with HIV in Italy

Cited by 21 publications

References 13 publications

Estimating Minimum Adult HIV Prevalence: A Cross-Sectional Study to Assess the Characteristics of People Living with HIV in Italy

Estimating Minimum Adult HIV Prevalence: A Cross-Sectional Study to Assess the Characteristics of People Living with HIV in Italy

Organ transplantation from “increased infectious risk donors”: the experience of the Nord Italia Transplant program - A retrospective study

La conta dei linfociti nel monitoraggio del paziente con infezione da HIV: evidenze per un impiego ragionato

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