Estimating national-level measles case–fatality ratios in low-income and middle-income countries: an updated systematic review and modelling study

Sbarra, Alyssa N.; Mosser, Jonathan F.; Jit, Mark; Ferrari, Matthew J.; Ramshaw, Rebecca E; O’Connor, Patrick; Krause, L Kendall; Rogowski, Emma L.B.; Portnoy, Allison

doi:10.1016/s2214-109x(23)00043-8

Cited by 18 publications

(9 citation statements)

References 19 publications

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“…A previously described model for estimating measles cases and deaths was updated with 2022 measles data and United Nations 2000–2022 population estimates †† ( 3 ). Data on case fatality rates from a publicly available statistical package (measlesCFR) §§ were used in the model to calculate estimates of measles mortality, based on previously published methodology ( 4 ). These activities were reviewed by CDC, deemed not research, and were conducted consistent with applicable federal law and CDC policy.…”

Section: Methodsmentioning

confidence: 99%

Progress Toward Measles Elimination — Worldwide, 2000–2022

Minta,

Ferrari,

Antoni

et al. 2023

MMWR Morb. Mortal. Wkly. Rep.

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105

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Section: Methodsmentioning

confidence: 99%

Progress Toward Measles Elimination — Worldwide, 2000–2022

Minta,

Ferrari,

Antoni

et al. 2023

MMWR Morb. Mortal. Wkly. Rep.

Self Cite

105

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Section: Articlementioning

confidence: 99%

“…Recently, several articles about measles outbreaks worldwide were published [ 1 , 2 ]. The high measles case-fatality rate in young children in low- and middle-income countries (LMIC) and importance of timely vaccination were stressed once more [ 2 ]. We acknowledge the recent backslide in childhood immunization worldwide [ 3 ], and the resulting emergence of multiple measles outbreaks.…”

Section: Articlementioning

confidence: 99%

Not only vaccine hesitancy, but also vaccination campaign hesitancy drives measles epidemics in conflict-torn eastern DR Congo

Van Brusselen,

Dubois,

Bindu

et al. 2024

Confl Health

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The COVID-19 pandemic and vaccine hesitancy are not the only causes of the increase in measles cases in low- and middle-income countries. Measles epidemics, like the recent one in eastern DRC, are often quickly halted by mass vaccination in ‘easy to reach’ refugee camps. However, governmental and humanitarian actors fail to respond effectively in ‘hard-to-reach’ areas like Masisi, frequently limiting themselves to more accessible areas close to big cities.

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“…Important milestones in the WHO strategy toward measles and rubella elimination [ 4 ] have been achieved globally during the last two decades, with significant reductions in the burden of both diseases, improved surveillance, and increased vaccine uptake in the national immunization programs. Nevertheless, measles outbreaks continue to occur periodically, due to persisting immunization gaps in the population, and the disease remains one of the leading causes of death in children worldwide [ 5 , 6 ].…”

Section: Introductionmentioning

confidence: 99%

Suboptimal MMR Vaccination Coverages—A Constant Challenge for Measles Elimination in Romania

Stanescu,

Ruta,

Cernescu

et al. 2024

Vaccines

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Measles is targeted for elimination since 2001, with a significant reduction in cases recorded worldwide, but outbreaks occur periodically due to immunization gaps. This study analyzes the evolution of vaccination coverage rates (VCRs) in Romania, a EU country with large measles epidemics during the last two decades, including an ongoing outbreak in 2023. Vaccination against measles has been part of the National Immunization Program since 1979, initially as a single dose, and from 1994 onwards it has had two doses. The initially high national VCRs of >97% gradually declined from 2010 onward and remained constantly under 90%, with further decreases during the COVID-19 pandemic. The lowest VCRs for both vaccine doses in the last decade were recorded in 2022 and were 83.4% for the first dose and 71.4% for the second dose, with significant differences among Romania’s 42 counties. Several factors contributed to this decline, including failure to attend the general practitioners’ offices, increased number of children lost to follow-up due to population movements, missed vaccination opportunities due to temporary medical contraindications, a surge in vaccine hesitancy/refusal, a decreasing number of general practitioners and discontinuities in vaccine supply. The persisting suboptimal VCRs in Romania threaten the progress toward measles elimination.

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Estimating national-level measles case–fatality ratios in low-income and middle-income countries: an updated systematic review and modelling study

Cited by 18 publications

References 19 publications

Progress Toward Measles Elimination — Worldwide, 2000–2022

Progress Toward Measles Elimination — Worldwide, 2000–2022

Not only vaccine hesitancy, but also vaccination campaign hesitancy drives measles epidemics in conflict-torn eastern DR Congo

Suboptimal MMR Vaccination Coverages—A Constant Challenge for Measles Elimination in Romania

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