Feature selection has gained its importance due to the voluminous nature of the data. Owing to the computational complexity of wrapper approaches, the poor performance of filtering techniques, and the classifier dependency of embedded approaches, hybrid approaches are more commonly used in feature selection. Hybrid approaches use filtering metrics to reduce the computational complexity of wrapper algorithms and are proved to yield better feature subset. Though filtering metrics select the features based on their significance, most of them are unstable and biased towards the metric used. Moreover, the choice of filtering metrics depends largely on the distribution of data and data types. Biomedical datasets contain features with different distribution and types adding to the complexity in the choice of filtering metric. We address this problem by proposing a stable filtering method based on rank aggregation in hybrid feature selection model with Improved Squirrel search algorithm for biomedical datasets. Our proposed model is compared with other well-known and state-of-the-art methods and the results prove that our model exhibited superior performance in terms of classification accuracy and computational time. The robustness of our proposed model is proved by conducting experiments on nine biomedical datasets and with three different classifiers.