Estimating perchlorate exposure from food and tap water based on US biomonitoring and occurrence data

Huber, D.; Blount, Benjamin C.; Mage, David T.; Letkiewicz, F.; Kumar, Amit; Allen, Ruth H.

doi:10.1038/jes.2010.31

Cited by 67 publications

(50 citation statements)

References 364 publications

(471 reference statements)

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“…A generic expression for estimating DI of a chemical using urinary biomarker data is given below: To minimise the effect of urine dilution, the urinary biomarker concentration data from spot urine analyses are adjusted using one of the following methods (Mage et al, 2004(Mage et al, , 2008Lakind and Naiman, 2008;Lakind et al, 2011;Huber et al, 2011). Based on the method employed, the urinary concentration and the adjustment factor terms in the above equation would change while all other terms remain the same.…”

Section: Estimation Of DI Using Urinary Biomarker Concentrationsmentioning

confidence: 99%

“…The creatinine adjustment approach (cf., Section 6.1.1) was used to estimate phthalate DIs using urinary metabolite data. The CER was estimated in individuals using Mage equations based on the height, weight and sex of the participants (Mage et al, 2008;Huber et al, 2011). Since the height and weight information were not collected in SFF study, a default value for CER applicable to pregnant women was used.…”

Section: Applications Of Reverse Dosimetry Tools In Human Health Riskmentioning

confidence: 99%

“…Like CHAP, Health Canada used creatinine correction approach (cf., Section 6.1.1) for deriving DI estimates. The CER s were derived in individuals using Mage equations (Mage et al, 2008;Huber et al, 2011). Median body mass indices were used for the respective population groups in both the CHMS and NHANES analyses.…”

Section: Applications Of Reverse Dosimetry Tools In Human Health Riskmentioning

confidence: 99%

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The role of human biological monitoring in health risk assessment

Gurusankar¹,

Yenugadhati

Krishnan

et al. 2017

IJRAM

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Human biological monitoring refers to the measurement of biomarkers in biological specimens. Advances in analytical chemistry together with an increased understanding of the potential toxicity of environmental chemicals have propelled the quest to identify and monitor chemicals and metabolites in human biological specimens. Many biomonitoring programs have provided valuable data on the presence of environmental chemicals in biological matrices. The availability of this large volume of biomonitoring data has increased the need to understand this information with respect to potential human health risks. This review summarises approaches for interpreting biomonitoring data in the context of population health and risk assessment. Moreover, the advantages and limitations of human biomonitoring approaches, major challenges in the interpretation of HBM data and the utility of human biomonitoring data in health risk assessment context are presented. Several knowledge gaps to improve the ability to interpret human biomonitoring data are discussed.

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Section: Estimation Of DI Using Urinary Biomarker Concentrationsmentioning

confidence: 99%

Section: Applications Of Reverse Dosimetry Tools In Human Health Riskmentioning

confidence: 99%

Section: Applications Of Reverse Dosimetry Tools In Human Health Riskmentioning

confidence: 99%

See 1 more Smart Citation

The role of human biological monitoring in health risk assessment

Gurusankar¹,

Yenugadhati

Krishnan

et al. 2017

IJRAM

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show abstract

“…Ухудшение экологической обстановки приводит к поступлению с пищей и водой соединений, которые не должны попадать в организм (например, перхлоратов) [2], а широкое использование в произ-водстве животноводческой продукции (мясо, птица, молоко) антибиотиков приводит к появлению новых инфекций, устойчивых к действию антибиотиков, и росту частоты развития внутрибольничных инфекций [3]. Все [7].…”

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Changes in Nutrition and Children’s Health

Nikolaeva¹

2013

Vopr. sovr. pediatr.

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“…퍼클로레이트는 암모늄 퍼클로레이트(NH4ClO4), 소 듐 퍼클로레이트(NaClO4), 칼륨 퍼클로레이트(KClO4), 퍼크 로릭 산(HClO4) 등의 다양한 염의 형태로 생산되며 물에서 화학적으로 안정하여 쉽게 분해되지 않고 용해도가 높으며 비휘발성이다. 대기, 토양, 지표수, 지하수 등에 1차적으로 유 입되어 음용수 및 농산물을 오염시키며 인체의 주요 노출 경 로로 보고되고 있다 (Ellington et al, 2001;Huber et al, 2011 Fig 1). (Huh et al, 2007).…”

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