Spanish is the fourth most spoken language in the world, and the majority of Spanish speakers have a Latin American origin. Reading aloud infrequently accentuated words has been established as a National Adult Reading Test-like method to assess premorbid intelligence in Spanish. However, several versions have been proposed and validated with small and selected samples, in particular geographical conditions, and they seldom derive a formula for IQ estimation with the Wechsler Adult Intelligence Scale (WAIS) Full-Scale IQ (FSIQ). The objective of this study was to develop equations to estimate WAIS-Third Edition (WAIS-III) FSIQ from the Word Accentuation Test-Revised (WAT-R), demographic variables, and their combination within diverse Latin American samples. Two hundred and forty participants from Argentina and Colombia, selected according to age and years of education strata, were assessed with the WAT-R, the WAIS-III, and a structured questionnaire about demographic and medical information. A combined approach including place of birth, years of education, and WAT-R provided the best equation, explaining 76% of IQ variance. These equations could be useful for estimating premorbid IQ in patients with Latin American Spanish as their birth language.