2018
DOI: 10.24171/j.phrp.2018.9.3.05
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Estimating the Incidence of Cases and Deaths Resulting from Hand, Foot and Mouth Disease and Its Related Socioeconomic Disease Burden in Republic of Korea (2010 – 2014)

Abstract: ObjectivesHand, Foot and Mouth disease (HFMD) is a highly contagious viral disease that affects young children and frequently causes epidemics. A vaccine is available in China (enterovirus 71) and, the Republic of Korea took the first step to develop a new vaccine. New vaccine development requires that disease burden is calculated in advance so the financial cost, morbidity and mortality can be measured.MethodsData from National Sentinel Surveillance and health insurance systems of 1 million claimants were use… Show more

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Cited by 9 publications
(4 citation statements)
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“…Mild symptoms usually recover well about a week after symptom treatment. However, when the symptoms of the disease are severe, conditions such as encephalitis and pulmonary edema may occur, which are life-threatening ( 5 ) and cause a significant financial burden to the patient's family ( 29 , 30 ).…”
Section: Relevant Sectionsmentioning
confidence: 99%
“…Mild symptoms usually recover well about a week after symptom treatment. However, when the symptoms of the disease are severe, conditions such as encephalitis and pulmonary edema may occur, which are life-threatening ( 5 ) and cause a significant financial burden to the patient's family ( 29 , 30 ).…”
Section: Relevant Sectionsmentioning
confidence: 99%
“…Furthermore, neurologic complications are associated with increased mortality, especially in children [ 3 ]. In South Korea, HFMD epidemics recur between April and August, and the annual economic burden is estimated to be US $100 million [ 4 5 ]. Seasonal HFMD epidemics have been a major public health concern in South Korea.…”
Section: Introductionmentioning
confidence: 99%
“…It is important to evaluate the HFMD surveillance system as it provides data for key epidemiological findings, including seasonality and economic burden [ 2 4 ]. Previous studies report a decline in HFMD notifications during the acute phase of the COVID-19 pandemic [ 11 12 ].…”
Section: Introductionmentioning
confidence: 99%
“…Hand-foot-mouth disease (HFMD) is an acute intestinal infectious disease which is caused by Enterovirus 71 (EV71), Coxsackie virus A16 (CA16), and other intestinal viruses 1,2 . It is mainly transmitted by direct contact or indirect contact with saliva, nasal mucus or other nasopharyngeal secretions of HFMD patients 3 .…”
Section: Introductionmentioning
confidence: 99%