2024
DOI: 10.1111/trf.17810
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Estimating the serological underrecognition of patients with weak or partial RHD variants

Glenn Ramsey,
Christina M. Barriteau

Abstract: BackgroundFor patients with weak or discrepant RhD RBC phenotypes, RHD genotyping is employed to determine need for RhD‐negative management. However, many RHD variants are type D‐negative or D‐positive. Serological recognition rates (RRs) of weak and partial RHD variants are poorly characterized.Study Design and MethodsFour US studies employing RHD genotyping for weak or discrepant RhD phenotypes provided data for race/ethnicity‐specific serological recognition. Three studies used microplate, and 1 used gel an… Show more

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