“…However, the extensive application of artificial neural network is affected by the amount of data necessary for development and validation of the model, and more importantly, the difficulty of expressing it as a universal model with coefficients and parameters. The first two models were advanced under the same theoretical assumption that the breakdown of the heat labile components is approximately as a first order chemical reaction, mathematically similar to the destruction of bacteria (Leonard, Merson, Marsh, & Heil, 1986). Nevertheless, this assumption was challenged by many studies and a more accurate, flexible and convenient WeLL model was argued to be able to provide a better choice for quantifying food thermal destruction of microorganisms, nutrients, and food enzymes (Peleg, 1999;Campanella & Peleg, 2001;Mafart et al, 2002;Peleg, Engel, Gonzalez-Martinez, & Corradini, 2002;Peleg, Corradini, & Normand, 2004;Corradini & Peleg, 2004a).…”