Estimation and Measurement of Biological Tissues Using Optical Simulation Method

Jagajothi, G.; Raghavan, S.

doi:10.2528/pierm09021604

Cited by 1 publication

(1 citation statement)

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“…In addition to their role in interpreting tissue polarimetry results, these measured optical properties may contribute to recent tissue optics compilations. [37][38][39][40] Polarized light imaging allows the construction of spatial maps in which the Mueller matrix derived parameters may be plotted. In Fig.…”

Section: Resultsmentioning

confidence: 99%

Quantitative correlation between light depolarization and transport albedo of various porcine tissues

et al. 2012

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Abstract. We present a quantitative study of depolarization in biological tissues and correlate it with measured optical properties (reduced scattering and absorption coefficients). Polarized light imaging was used to examine optically thick samples of both isotropic (liver, kidney cortex, and brain) and anisotropic (cardiac muscle, loin muscle, and tendon) pig tissues in transmission and reflection geometries. Depolarization (total, linear, and circular), as derived from polar decomposition of the measured tissue Mueller matrix, was shown to be related to the measured optical properties. We observed that depolarization increases with the transport albedo for isotropic and anisotropic tissues, independent of measurement geometry. For anisotropic tissues, depolarization was higher compared to isotropic tissues of similar transport albedo, indicating birefringence-caused depolarization effects. For tissues with large transport albedos (greater than ∼0.97), backscattering geometry was preferred over transmission due to its greater retention of light polarization; this was not the case for tissues with lower transport albedo. Preferential preservation of linearly polarized light over circularly polarized light was seen in all tissue types and all measurement geometries, implying the dominance of Rayleigh-like scattering. The tabulated polarization properties of different tissue types and their links to bulk optical properties should prove useful in future polarimetric tissue characterization and imaging studies.

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Section: Resultsmentioning

confidence: 99%