Response of wheat (Triticum aestivum L., cv. Shatabdi) to irrigation water of five salinity levels was investigated at the Bangladesh Agricultural University (BAU) farm with a view to search for a possible advantageous salinity level for the crop. The experiment comprised five treatments − I 1 : irrigation by fresh water of background salinity 0.385 dS m −1 (control) and I 2 − I 5 : irrigation by synthetic saline water (prepared by mixing sodium chloride salt with fresh water) of electrical conductivity (EC) 4, 7, 10 and 13 dS m −1 (at 25 o C), respectively. Wheat was grown under three irrigations applied at maximum tillering, booting and milking/grain filling stages, and with recommended fertilizer dose. Irrigation water of EC ≥10 dS m −1 significantly (p = 0.05) suppressed most growth and yield attributes, and yield of wheat compared to irrigation by fresh water (I 1 ). An attention-grabbing observation was that irrigation by saline water of 4 dS m −1 (I 2 ) contributed positively to the crop attributes. Leaf area index (LAI), spike length, spikelets and grains per spike, 1000-grain weight and above ground dry matter (ADM) of wheat increased by 1.9−3.4, 0.9, 2.6, 7.4, 2.1 and 2.8−6.0%, respectively in I 2 compared to the control. The improvement in the LAI and ADM in I 2 was significant over I 1 . Because of the largest spike density, the utmost grain (3.85 t ha −1 ), straw (5.09 t ha −1 ) and biomass (8.93 t ha −1 ) yields of wheat were however obtained under I 1 . The proposition of the advantageous irrigation water salinity level of 4 dS m −1 thus warrants further investigation.