Estimation of age from the femur of Japanese cadavers

Watanabe, Yutaka; Konishi, Masayoshi; Shimada, M.; Ohara, Hidetsugu; Iwamoto, Sotaro

doi:10.1016/s0379-0738(98)00136-4

Cited by 49 publications

(42 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Indeed, in an earlier study we found rather low inter and intra observer agreement rates, effectively being able to only identify secondary osteons reliably [15]. We tried to address this problem by various histological staining techniques, but in our opinion this did not improve the identification of the features [26], although other investigators have reported improvement with staining [27]. Rather than quantifying secondary osteons and osteon fragments per se, it has been suggested to add the counts of the two structures (representing the so-called osteon population density) [14,28,29].…”

Section: Discussionmentioning

confidence: 80%

Assessment of age at death by microscopy: Unbiased quantification of secondary osteons in femoral cross sections

Lynnerup

Frøhlich

Thomsen

2006

Forensic Science International

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 80%

Assessment of age at death by microscopy: Unbiased quantification of secondary osteons in femoral cross sections

Lynnerup

Frøhlich

Thomsen

2006

Forensic Science International

View full text Add to dashboard Cite

“…Experiments employed in these studies included both scanning electron microscopy (SEM) [16] and nanoindentation [17] to analyse microstructural constituents of human cortical bone and their mechanical properties, in order to understand theirs functions and mechanisms in the fracture process. Watanabe [3] tested with X-ray and light microscopy cortical-bone specimens of 72 male and 26 female cadavers' donors, whose age range was from 9 to over 90. The morphological size of osteons and Haversian canals was measured, using collection data to estimate the age of bone.…”

Section: Introductionmentioning

confidence: 99%

Effect of micromorphology of cortical bone tissue on crack propagation under dynamic loading

Wang

Gao

Abdel-Wahab

et al. 2015

EPJ Web of Conferences

View full text Add to dashboard Cite

Abstract. Structural integrity of bone tissue plays an important role in daily activities of humans. However, traumatic incidents such as sports injuries, collisions and falls can cause bone fracture, servere pain and mobility loss. In addition, ageing and degenerative bone diseases such as osteoporosis can increase the risk of fracture [1]. As a composite-like material, a cortical bone tissue is capable of tolerating moderate fracture/cracks without complete failure. The key to this is its heterogeneously distributed microstructural constituents providing both intrinsic and extrinsic toughening mechanisms. At micro-scale level, cortical bone can be considered as a four-phase composite material consisting of osteons, Haversian canals, cement lines and interstitial matrix. These microstructural constituents can directly affect local distributions of stresses and strains, and, hence, crack initiation and propagation. Therefore, understanding the effect of micromorphology of cortical bone on crack initiation and propagation, especially under dynamic loading regimes is of great importance for fracture risk evaluation. In this study, random microstructures of a cortical bone tissue were modelled with finite elements for four groups: healthy (control), young age, osteoporosis and bisphosphonate-treated, based on osteonal morphometric parameters measured from microscopic images for these groups. The developed models were loaded under the same dynamic loading conditions, representing a direct impact incident, resulting in progressive crack propagation. An extended finite-element method (X-FEM) was implemented to realize solution-dependent crack propagation within the microstructured cortical bone tissues. The obtained simulation results demonstrate significant differences due to micromorphology of cortical bone, in terms of crack propagation characteristics for different groups, with the young group showing highest fracture resistance and the senior group the lowest.

show abstract

“…These factors will, in turn, affect the accuracy of histomorphological age-estimation methods. Osteon size (area) was identified as possibly exhibiting ancestral/population differences (Cho et al, 2002;Havill, 2003;Watanabe et al, 1998). It was reported to differ by age and physical activity (Landeros and Frost, 1964;Ortner, 1975;Paine and Godfrey, 1997;Pirok et al, 1966;Stout and Simmons, 1979;Takahashi et al, 1965;Thompson and Galvin, 1983).…”

mentioning

confidence: 99%

Secondary osteon and Haversian canal dimensions as behavioral indicators

Pfeiffer

Crowder

Harrington

et al. 2006

Am. J. Phys. Anthropol.

124

View full text Add to dashboard Cite

Variation in the size of structures within mature cortical bone is relevant to our understanding of apparent differences between human samples, and it is relevant to the development of histologically based age-estimation methods. It was proposed that variation may reflect effects of physical activity, through biomechanical and/or metabolic mechanisms. If these factors are local, femoral osteon area (On.Ar) should be more histologically variable than On.Ar in ribs. Ribs should show a higher variation in Haversian canal area (H.Ar) if they are sites of more remodeling activity and hence of arrested refilling of secondary osteons at time of death. This study compares On.Ar and H.Ar of secondary osteons from femora (15) and ribs (29) from 44 Holocene (Later Stone Age) foragers from South Africa (M = 19, F = 25) to values from paired femora and ribs from historic samples (Spitalfields and St. Thomas, 20 pairs from each). Fixed-effects analysis of variance demonstrates rib On.Ar to be significantly smaller than femur, but with no sex or age effects. The femur-to-rib On.Ar ratio is lower for the Holocene foragers than for the two modern samples because of relatively large rib On.Ar. Femora and ribs from the same skeleton normally show femoral On.Ar larger than rib On.Ar (37/44 pairs). Mean femoral values of On.Ar are more diverse than rib On.Ar values, but within-sample coefficients of variation are similar. Values for H.Ar are highly variable and do not reflect anatomical site, age, sex, or population effects. The patterning of osteon size does not appear to be linked to physical activity or to different rates of metabolic activity within the skeleton, at least not in a straightforward way.

show abstract

Estimation of age from the femur of Japanese cadavers

Cited by 49 publications

References 13 publications

Assessment of age at death by microscopy: Unbiased quantification of secondary osteons in femoral cross sections

Assessment of age at death by microscopy: Unbiased quantification of secondary osteons in femoral cross sections

Effect of micromorphology of cortical bone tissue on crack propagation under dynamic loading

Secondary osteon and Haversian canal dimensions as behavioral indicators

Contact Info

Product

Resources

About