Estimation of calcium and magnesium in serum and urine by atomic absorption spectrophotometry

Thin, Christian; Thomson, Patricia A. G.

doi:10.1136/jcp.20.3.280

Cited by 14 publications

(5 citation statements)

References 8 publications

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“…Thin and Thomson, studied 138 male and female normal adults aged 18-63 years, have reported a range of 1.83-2.43 mg/dL for serum Mg concentrations [12], values that are very Fig. 1 Histograms showing the normal distribution of serum magnesium concentrations in men and women close to our results.…”

Section: Discussionsupporting

confidence: 86%

“…However, relatively few studies, all in developed countries, have been carried out on the determination of reference intervals for serum or blood Mg concentrations [4,[10][11][12][13] and currently, there are no generally accepted reference values for serum Mg levels according to the International Federation of Clinical Chemistry (IFCC) guidelines [7].…”

Section: Introductionmentioning

confidence: 99%

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Reference Values for Serum Magnesium Levels in Young Adult Iranian Subjects

Ghasemi

Zahediasl

Azizi

2010

Biol Trace Elem Res

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This study aims at determining the reference values for serum magnesium (Mg) concentrations in Iranian adults. Serum Mg level was measured using flame atomic absorption spectrometry in 491 subjects (233 men and 258 women), aged 20-50 years, randomly selected from a population-based study. The International Federation of Clinical Chemistry guidelines and the robust method were used for determining the reference values. The 95% reference values for serum Mg concentration were 1.83-2.49, 1.79-2.48, and 1.83-2.55 mg/dL in men, women, and total population, respectively. The prevalences of hypo- and hypermagnesemia, according to the reference values obtained in the current study, were 2.5% and 4.0%, respectively. In conclusion, this study reports serum Mg reference values based on current standards in a large healthy population of young Iranian adults.

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Section: Discussionsupporting

confidence: 86%

Section: Introductionmentioning

confidence: 99%

Reference Values for Serum Magnesium Levels in Young Adult Iranian Subjects

Ghasemi

Zahediasl

Azizi

2010

Biol Trace Elem Res

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“…Calcium as well as magnesium are very important for metabolism at the cellular level and are mandatory for muscle contraction, also for neuronal activity making it very essential in pregnancy 18,19 . Mitchell et.…”

Section: Discussionmentioning

confidence: 99%

Effect of Minerals on Markers of Risk of Pre-Eclampsia in Pregnant Women: A Hospital Based Study

2020

IJFMT

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Introduction: Pregnancy specific complication characterised by hypertension, proteinuria, after 20 weeks of the gestation, and along with various signs of damage to organ systems, haemolysis, elevated levels of liver enzymes and low platelet count (HELLP syndrome) is collectively termed as eclampsia.Method: Cross-sectional study with 3 groups of pregnant women, were taken followed by inclusion and exclusion criteria for characterisation. The study was approved by ethical board of DMIMSU. Minerals and their relationship were estimated using different method. Preeclamptic group with and without supplementation and pregnant women without preeclampsia were included in the study. Significant differences were seen in Na+, K+, Ca, Mg, Se, and Mn when compared with each group. Result and Observation:The levels of K were increased significantly (P < 0.001) in pre-eclamptic group as compared to control group. There was significant change in levels of Mn when pre-eclamptic group was compared to control. Mn was also found to decrease significantly (P < 0.001) in cases as compared to control. However, the levels of Se, Mg, Ca and Na between cases and control were not highly significant. In supplementation and without supplementation group, Significant differences were seen in levels of Na, K, Ca and very significant difference was seen in levels of Mn. (p<0.0001). Conclusion:Pre-eclamptic pregnant women have higher levels of serum potassium and our finding on Mn, an essential trace mineral, provides new insight into a potentially modifiable way to prevent preeclampsia. In multi-ethnic, predominantly urban and low-income pregnant women high level of Mn is associated with pre-eclampsia.

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“…in several biological fluids in humans for many years by use of several methods but more recently by atomic absorption spectrophotometry and inductively coupled emission spectroscopy [10][11][12][13][14][15][16][17][18][19][20][21][22]. These measurements have usually been made in reference to physiological changes or pathological conditions in single biological fluids.…”

Section: Measurements Of Calcium and Magnesium Have Been Madementioning

confidence: 99%

Calcium and Magnesium Levels Change in Relationship to Variations in Usual Dietary Nutrient Intake

Henkin¹

2018

jnhfs

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Objective: Changes in nutrient intake induce changes in calcium and magnesium metabolism. However, studies dealing with these changes were usually performed by addition of one specific nutrient to initiate changes in either calcium or magnesium in only one biological fluid, usually blood plasma or urine. We were interested in evaluating changes in both calcium and magnesium levels in several biological fluids simultaneously in relationship to usual intake of a wide range of dietary nutrients since this type of study has not been previously performed. Methods: Calcium and magnesium in blood plasma, urine and saliva and magnesium in erythrocytes were measured by flame aspiration atomic absorption spectrophotometry in 253 subjects, 150 women and 103 men in relationship to their usual dietary intake of calcium, magnesium, sodium, potassium, phosphorus, carbohydrate, fat, fiber, protein, vitamin D, vitamin C and total calories. Dietary nutrient intake was calculated by careful, systematic analysis of all food and fluids taken over three typical days by performance of computer based dietary analysis. Results: Complex changes occurred in calcium and magnesium levels in some but not all biological fluids as usual dietary nutrient intake varied. As sodium, potassium and total calorie intake increased urinary calcium excretion increased. As sodium, potassium, vitamin D and protein intake increased urinary magnesium excretion increased. As sodium intake increased salivary magnesium decreased. Conclusions: These studies demonstrate that calcium and magnesium levels in blood plasma, urine, saliva and nasal mucus are altered following variations in the usual intake of several dietary nutrients. These results can assist in forming a nutritional foundation upon which variations in the usual dietary intake of several nutrients alter calcium and magnesium levels in several biological fluids.

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Estimation of calcium and magnesium in serum and urine by atomic absorption spectrophotometry

Cited by 14 publications

References 8 publications

Reference Values for Serum Magnesium Levels in Young Adult Iranian Subjects

Reference Values for Serum Magnesium Levels in Young Adult Iranian Subjects

Effect of Minerals on Markers of Risk of Pre-Eclampsia in Pregnant Women: A Hospital Based Study

Calcium and Magnesium Levels Change in Relationship to Variations in Usual Dietary Nutrient Intake

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