Estimation of case-fatality rate in COVID-19 patients with hypertension and diabetes mellitus in the New York state: a preliminary report

Ge, Yang; Sun, Shengzhi; Shen, Ye

doi:10.1017/s0950268821000066

Cited by 13 publications

(12 citation statements)

References 7 publications

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“…Our results suggest that elevated HRs associated with comorbidities are more marked in the younger age groups and, as reported by Ge et al 14 , the young population with comorbidities should also be considered as a vulnerable group. In addition, our results suggest a strong association between the level of education and fatality risk due to COVID-19, showing that strategies for the prevention and management of the disease also need to consider the social aspects of the population.…”

supporting

confidence: 86%

Comorbidities and the risk of death among individuals infected by COVID-19 in Espírito Santo, Brazil

Martinez

Aragon

Pontes

et al. 2021

Rev. Soc. Bras. Med. Trop.

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Introduction: We investigated the association of self-reported comorbidities with fatality risk among individuals infected with Coronavirus disease 2019 in Espírito Santo State, Brazil. Methods: We included 212,620 individuals, ≥30 years old. The data were obtained from the COVID-19 panel. Kaplan-Meier curves and Cox regression model were used. Results: COVID-19-positive individuals presenting with chronic conditions were at a higher risk of fatality than individuals without these comorbidities. Age had a significant effect on these relationships. Conclusions: Comorbidities were associated with an increased risk of fatality. Middle-aged people (30-59 years) with comorbidities should also be considered as a vulnerable group.

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supporting

confidence: 86%

Comorbidities and the risk of death among individuals infected by COVID-19 in Espírito Santo, Brazil

Martinez

Aragon

Pontes

et al. 2021

Rev. Soc. Bras. Med. Trop.

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“…In contrast, a whole-population study from England found only 5.2% DM between COVID-19 patients [36] . In American countries, the US presented the highest prevalence rates, approximately 12% to 30% [37] , [38] , while in Latin America, DM has been reported in 8.3% of COVID-19 cases [39] . Additionally, studies from London and the US said that nonwhite patients with DM were the majority among COVID-19 cohorts, with 72% and 56%, respectively [40] , [41] .…”

Section: Introductionmentioning

confidence: 97%

“…Additionally, studies from London and the US said that nonwhite patients with DM were the majority among COVID-19 cohorts, with 72% and 56%, respectively [40] , [41] . Furthermore, the prevalence of DM in COVID-19 patients has been higher in adults over 50 years of age, especially in those aged 65-70 years [29] , [30] , [33] , [37] , [42] . Other studies indicate that male patients with DM had a significant prevalence (50–60%) among COVID-19 patients [31] , [42] , [43] .…”

Section: Introductionmentioning

confidence: 99%

The underlying mechanisms for severe COVID-19 progression in people with diabetes mellitus: a critical review

Figueroa-Pizano¹,

Campa-Mada²,

Carvajal-Millan³

et al. 2021

AIMSPH

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<abstract> <p>Diabetes mellitus (DM) has a high incidence of comorbidities among patients with severe coronavirus disease 2019 (COVID-19). The elevated prevalence of DM in the world population makes it a significant risk factor because diabetic individuals appear to be prone to clinical complications and have increased mortality rates. Here, we review the possible underlying mechanisms involved in DM that led to worse outcomes in COVID-19. The impacts of hyperglycemia side effects, secondary comorbidities, weakened innate and adaptive immunity, chronic inflammation, and poor nutritional status, commonly present in DM, are discussed. The role of the SARS-CoV-2 receptor and its polymorphic variations on higher binding affinity to facilitate viral uptake in people with DM were also considered. Clinical differences between individuals with type 1 DM and type 2 DM affected by COVID-19 and the potential diabetogenic effect of SARS-CoV-2 infection were addressed.</p> </abstract>

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“…Pre-existing health conditions may exacerbate the severity of SARS-CoV-2 disease. These conditions include old age [ 4 ], hypertension, coronary artery disease, and diabetes mellitus [ 5 , 6 , 7 ]. Moreover, weather conditions, such as a cold climate, humidity [ 8 , 9 ], and environmental pollution are leading causative factors in increasing SARS-CoV-2 cases and deaths [ 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

Comparison of Generalized Anxiety and Sleep Disturbance among Frontline and Second-Line Healthcare Workers during the COVID-19 Pandemic

Meo

Alkhalifah

Alshammari

et al. 2021

IJERPH

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Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2) infection, also known as COVID-19, has developed into an alarming situation around the world. Healthcare workers are playing the role of frontline defense to safeguard the lives of everyone during the COVID-19 pandemic. The present study aimed to investigate the anxiety levels and sleep quality among frontline and second-line healthcare workers during the COVID-19 pandemic. In this cross-sectional study, a validated, self-administered, electronic questionnaire was distributed through email to healthcare workers. The selection of 1678 healthcare workers was based on a convenience sampling technique. The General Anxiety Disorder-7 (GAD-7) and Pittsburgh Sleep Quality Index (PSQI) instrument scales were used to assess healthcare workers’ anxiety levels and sleep quality during the COVID-19 pandemic. Out of 1678 respondents, 1200 (71.5%) were frontline healthcare workers, while 478 (28.5%) were second-line healthcare workers. Among all the healthcare workers, 435 (25.92%) were experiencing moderate to severe anxiety. Among them, 713 (59.4%) frontline healthcare workers were experiencing anxiety in comparison with 277 (57.9%) second-line healthcare workers. Severe anxiety symptoms were seen in 137 (11.41%) frontline healthcare workers compared to 44 (9.20%) second-line healthcare workers. In total, 1376 (82.0%) healthcare workers were found to have poor sleep quality; 975 (58.10%) were frontline, and 407 (23.89%) were second-line healthcare workers. The highest poor sleep quality levels were found among 642 (84.6%) of the healthcare workers who work in frontline areas (emergency departments, intensive care units, and wards) compared to 734 (79.9%) of the healthcare workers who work in second-line areas. These findings provide a substantial contribution to the consolidation of evidence concerning the negative impact of the pandemic on the mental health of healthcare workers (HCWs). These results have established an association that the COVID-19 pandemic causes larger negative psychological symptoms in frontline healthcare workers, such as severe anxiety and poor sleep quality. Preventive measures to minimize anxiety levels and maintain sleep quality, addressing this issue nationally and globally, are essential to support the healthcare workers who are sacrificing their mental health for the future of our nations.

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Estimation of case-fatality rate in COVID-19 patients with hypertension and diabetes mellitus in the New York state: a preliminary report

Cited by 13 publications

References 7 publications

Comorbidities and the risk of death among individuals infected by COVID-19 in Espírito Santo, Brazil

Comorbidities and the risk of death among individuals infected by COVID-19 in Espírito Santo, Brazil

The underlying mechanisms for severe COVID-19 progression in people with diabetes mellitus: a critical review

Comparison of Generalized Anxiety and Sleep Disturbance among Frontline and Second-Line Healthcare Workers during the COVID-19 Pandemic

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