Background: Importance: Menopause accompanied by many signs and symptoms in the women's life. Objective: This study aims to review impact of menopause on the health of menopausal women in Iran. method: This review performed in accordance with the PRISMA guidelines. We searched, including PubMed, Web of Science (ISI), Scopus, Ovid, and the Iranian Clinical Trial Registry and Magiran, SID from January 1990 to January 2020. The quality of the articles was assessed the consort tool in clinical trials and STORB tool for observational research and PRISMA tool for systematic review. Findings: In total 2759 articles were obtained by searching in databases. Finally23 study selected to evaluate. According to the studies, Women's experiences of physical effects, negative emotions, negative attitudes, how adjustment, worries and psychological effects cause severity of menopausal symptoms and, as the age of postmenopausal women increases, the severity of physical and psychological symptoms decreases. education is one of the important factors that achieve healthy life style, increase knowledge and improve performance in order to improve the quality of life and menopausal health in women.Conclusion: attitudes toward menopause are influenced by the beliefs and culture of society. Thus, menopause more than a physiological phenomenon is a cultural phenomenon