Estimation of optical rotation of chiral molecules with weak measurements

Qiu, Xiaodong; Xie, Linguo; Liu, Xiong; Luo, Lan; Zhang, Zhiyou; Du, Jia

doi:10.1364/ol.41.004032

Cited by 115 publications

(46 citation statements)

References 29 publications

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“…Using the weak measurements, the tiny shift can be observed with the desirable accuracy leading to the corresponding physical parameters be determined. For example, the photonic SHE has been used for measuring the thickness of nanometal films 22 , identifying the graphene layers 23 , detecting the strength of axion coupling of topological insulators 24 , and estimating the optical rotation of chiral molecules 25 .…”

Section: Introductionmentioning

confidence: 99%

Photonic spin Hall effect enabled refractive index sensor using weak measurements

Zhou

Sheng

Ling

2018

Sci Rep

136

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In this work, we theoretically propose an optical biosensor (consists of a BK7 glass, a metal film, and a graphene sheet) based on photonic spin Hall effect (SHE). We establish a quantitative relationship between the spin-dependent shift in photonic SHE and the refractive index of sensing medium. It is found that, by considering the surface plasmon resonance effect, the refractive index variations owing to the adsorption of biomolecules in sensing medium can effectively change the spin-dependent displacements. Remarkably, using the weak measurement method, this tiny spin-dependent shifts can be detected with a desirable accuracy so that the corresponding biomolecules concentration can be determined.

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Section: Introductionmentioning

confidence: 99%

Photonic spin Hall effect enabled refractive index sensor using weak measurements

Zhou

Sheng

Ling

2018

Sci Rep

136

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“…In recent years, weak measurement has shown great superiority in numerous high precision measurements, such as phase measurement [2,3], velocity measurement [4], temperature sensing [5], reflection angle of optic beam [6], photonic spin Hall effect [7], Goos-Hänchen and Imbert-Fedorov shifts [8,9], optical rotation [10] and detection of a trapped electron [11]. Besides, weak measurement also presents great potential in biomolecule detection by inducing a weak interaction between the system and meter with analytes or biochemical reactions.…”

Section: Lettermentioning

confidence: 99%

A differential weak measurement system based on Sagnac interferometer for self-referencing biomolecule detection

Guan

et al. 2017

J. Phys. D: Appl. Phys.

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A differential weak measurement system was presented, exhibiting the self-referencing function for biomolecule real time detection as a label-free optical biosensor. We built a Sagnac interferometer, which limited horizontal (H) and vertical (V) polarization to propagating along the common path but in opposite directions to realize weak measurements with two measuring channels installed in two corners of this Sagnac interferometer. By introducing two half wave plates into the system alternately with the two channels to convert between H and V polarization, we obtained a differential measurement for phase delay, which could quantitatively characterize the refractive index change corresponding to the concentration of samples in the channels. With this system, a real time monitor of molecule concentration in the dialysis process was accomplished, demonstrating the function of self-referencing, which is important for optical label-free molecule detection in a complex biological sample solution.

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“…With proper pre-selection and post-selection, this slight offset can be amplified and eventually be read out from the pointer received by the detector, which is the so-called weak value amplification. In recent years, weak measurements have shown great advantages in many high-precision measurements such as Goos-Hänchen and Imbert-Fedorov shifts [3,4], the photonic spin Hall effect [5], phase measurement [6,7], velocity measurement [8], temperature sensing [9], reflection angle of light beam [10], and optical rotation [11]. Differential detection methods are important in high precision measurements, also as a self-compensating switchable measurement method where dielectric properties are highly important.…”

Section: Introductionmentioning

confidence: 99%

A Differential Detection Method Based on a Linear Weak Measurement System

Xiong

Guan

et al. 2019

Sensors

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Self-reference detection is necessary and important to a biosensor. The linear weak measurement system based on total internal reflection has attracted widespread attention due to its high stability, label-free detection, and easy integration. In this paper, we propose a differential detection method based on the linear total internal reflection weak measurement system. We introduce the half-wave plate (HWP) to convert the H light and the V light to each other, thereby obtaining the difference in phase change of the optical path before and after the HWP. Experiments show that the system can not only achieve differential detection, but also has high stability. The linear differential weak measurement system proposed in this paper not only provides a new differential measurement method for real-time biosensors, but also enriches the types of weak measurement sensors.

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Estimation of optical rotation of chiral molecules with weak measurements

Cited by 115 publications

References 29 publications

Photonic spin Hall effect enabled refractive index sensor using weak measurements

Photonic spin Hall effect enabled refractive index sensor using weak measurements

A differential weak measurement system based on Sagnac interferometer for self-referencing biomolecule detection

A Differential Detection Method Based on a Linear Weak Measurement System

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