Estimation of oxidant, antioxidant and metabolic biomarkers in sera of diabetic rats administrated with parsley leaves extract and its isolated apigenin

Ibrahiem, Aveen A.; Mosa, Azzam A.; Mohammed, Lina Y.

doi:10.1016/j.nutos.2024.02.003

Clinical Nutrition Open Science

2024

DOI: 10.1016/j.nutos.2024.02.003

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Estimation of oxidant, antioxidant and metabolic biomarkers in sera of diabetic rats administrated with parsley leaves extract and its isolated apigenin

Aveen A. Ibrahiem,

Azzam A. Mosa,

Lina Y. Mohammed

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Renal health benefits and therapeutic effects of parsley (Petroselinum crispum): a review

Alobaidi

2024

Front. Med.

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Parsley (Petroselinum crispum) has been used in traditional medicine for its diverse health benefits, and recent research highlights its potential in promoting renal health due to its bioactive compounds. This review focuses on evaluating the renal health benefits and therapeutic effects of parsley, addressing the growing interest in natural interventions for kidney-related conditions. It aims to consolidate existing evidence while identifying research gaps to support parsley’s integration into renal health management. A systematic review of scientific databases was conducted, identifying relevant studies on parsley’s biochemical properties, including flavonoids, phenolic acids, terpenoids, and essential oils, which contribute to antioxidant, anti-inflammatory, diuretic, and nephroprotective effects. Animal studies demonstrated reductions in oxidative stress, improvements in metabolic biomarkers, and enhanced renal function, while limited human studies revealed modest improvements in urinary composition and renal health markers. However, parsley’s safety profile, particularly at high doses, requires further investigation, including potential herb-drug interactions and safety during pregnancy. This review highlights parsley’s therapeutic potential as a natural agent for renal health and underscores the need for robust clinical trials, long-term safety evaluations, and standardized methodologies to validate its clinical significance.

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Renal health benefits and therapeutic effects of parsley (Petroselinum crispum): a review

Alobaidi

2024

Front. Med.

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Estimation of oxidant, antioxidant and metabolic biomarkers in sera of diabetic rats administrated with parsley leaves extract and its isolated apigenin

Cited by 1 publication

References 41 publications

Renal health benefits and therapeutic effects of parsley (Petroselinum crispum): a review

Renal health benefits and therapeutic effects of parsley (Petroselinum crispum): a review

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