Estimation of renal function in patients with chronic kidney disease

Kooman, Jeroen P.

doi:10.1002/jmri.21970

Cited by 28 publications

(16 citation statements)

References 38 publications

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“…Clinical data, such as gender, age, and stone components, were collected. Renal function was evaluated with eGFR using the modification of diet in renal disease formula [8,9]. The stone components were analyzed by Fourier transform infrared spectroscopy [10].…”

Section: Methodsmentioning

confidence: 99%

Renal function in patients with urinary stones of varying compositions

Chou

Hsu

et al. 2011

The Kaohsiung J of Med Scie

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Kidney stones are a potential risk factor for chronic kidney disease. The impact of different urinary stone components on renal function is unknown. In this study, we retrospectively reviewed 1,918 medical records of patients with urolithiasis. The renal function was evaluated as estimated glomerular filtration rate. All the stones were analyzed by Fourier transform infrared spectroscopy. The patients were divided into five groups according to the stone components. Statistical analysis was performed with analysis of variance. All the patients with stones had Stage 2-3 chronic kidney disease. The patients with uric acid and struvite stones had significantly lower estimated glomerular filtration rate compared with those having other stone components (p<0.01). Furthermore, the patients with calcium-containing stones (calcium oxalate and calcium phosphate) had significantly better renal function than those with non-calcium-containing stones (struvite and uric acid, p<0.01). Patients with urolithiasis had decreased renal function, and the impact of renal function varied depending on the stone components. We conclude that stone analysis is important in predicting the change in renal function in patients with urolithiasis. Moreover, the patients with non-calcium-containing stones, such as struvite and uric acid stones, should be carefully evaluated and treated to preserve their renal function.

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Section: Methodsmentioning

confidence: 99%

Renal function in patients with urinary stones of varying compositions

Chou

Hsu

et al. 2011

The Kaohsiung J of Med Scie

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“…Patients were categorized into five stages (hereafter referred to as CKDue stages) following the National Kidney Foundation Kidney Disease Outcome Quality Initiative guidelines [11] and based on the latest glomerular filtration rate (GFR). The modified diet in renal disease (MDRD) formula [GFR (ml/min/1.73 m 2 ) = 186 9 Scr -1.154 9 (Age) -0.203 9 (0.742 if female) 9 (1.212 if African American)] using Serum creatinine (Scr) levels was used to estimate GFR [12]. Glomerular filtration is considered to be the best estimate of kidney function.…”

Section: Ckdue Patientsmentioning

confidence: 99%

Evidence of tubular damage in the very early stage of chronic kidney disease of uncertain etiology in the North Central Province of Sri Lanka: a cross-sectional study

Nanayakkara

Senevirathna

Karunaratne

et al. 2011

Environ Health Prev Med

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Background In the North Central Province of Sri Lanka, chronic kidney disease of uncertain etiology (CKDue) has increased markedly over the past 15-20 years. Methods From around 4,700 patients who were followed up, 106 affected patients who visited two local clinics in the endemic area for CKDue on August 10, 2009 and 10 pedigrees of 10 of these cases with familial clustering of CKDue participated in this study. Urine samples, collected from affected patients (n = 106), unaffected relative controls (n = 81), and Japanese controls (n = 50), were analyzed for two tubular markers: a1-microglobulin and N-acetyl-b-D-glucosaminidase. Urine samples from patients with CKDue stages 1-4 (n = 101) and all the samples from unaffected relatives and Japanese controls were analyzed for urinary cadmium concentration. Results Urinary excretion of a1-microglobulin was elevated even in the earliest stage of CKDue compared with its levels in unaffected relative controls. Urinary excretion of N-acetyl-b-D-glucosaminidase was elevated only in stage 5. In contrast, urinary cadmium excretion was similar in CKDue patients and in the unaffected relative controls, and levels in both these groups were significantly lower than the level in the Japanese controls. All levels were below the threshold level for renal toxicity, indicating the absence of any evidence of cadmium toxicity. Conclusions The present study indicates that renal tubular damage occurs in the very early stage of CKDue and demonstrates the existence of familial clustering,

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“…Sie wird in der Praxis entweder aus dem 24 h-Urin berechnet oder als MDRD(modification of diet in renal disease)-GFR, als CKD-EPI(Chronic Kidney Disease Epidemiology Collaboration)-Formel oder nach der CockroftGault-Formel abgeschätzt. Die GFR beträgt bei nierengesunden Patienten 90-130 ml/min/1,73 m 2 [8].…”

Section: Bedeutung Und Pathophysiologieunclassified

Multiples Myelom

Goldschmidt

Weisel

2016

Nephrologe

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Das Multiple Myelom (MM) ist eine maligne Erkrankung der Plasmazellen und die häufigste monoklonale Erkrankung der Plasmazellen. Das MM sollte inhaltlich und sprachlich streng vom Plasmozytom getrennt werden, welches aufgrund der lokalen Begrenzung des Tumors durch Bestrahlung und/oder Operation in ca. 50 % der Patienten geheilt werden kann. Das MM ist eine Systemerkrankung und wird mit Chemotherapie, Glukokortikoiden und/ oder mit neuen Medikamenten wie Proteasomeninhibitoren oder immunmodulierenden Substanzen behandelt. Trotz einer Verlängerung der Lebenserwartung der Myelompatienten von 3 bis 4 Jahre auf 6 bis 8 Jahre ist das MM meist immer noch lebensbegrenzend.

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Estimation of renal function in patients with chronic kidney disease

Cited by 28 publications

References 38 publications

Renal function in patients with urinary stones of varying compositions

Renal function in patients with urinary stones of varying compositions

Evidence of tubular damage in the very early stage of chronic kidney disease of uncertain etiology in the North Central Province of Sri Lanka: a cross-sectional study

Multiples Myelom

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