A complete homogeneous earthquake catalogue is prepared to estimate seismicity parameters and their spatial-temporal variation in nine seismogenic source zones for Northeast India. The value of seismicity parameters like a-value, b-value, and MC value i.e., 7.37, 0.93(± 0.013), and 4.6, respectively have been estimated from the frequency-magnitude distribution. Moreover, the maximum-likelihood method has been utilized to map the spatial variation of the above parameters. The spatial variation of low b-values is dominant in the Indo-Burman Range, the Main Boundary Thrust, and the vicinity of the Sagaing fault. High seismic activity rate has been obtained in the Indo-Burman range as observed from spatial variation of a-value parameter. Furthermore, the return periods and the annual probability of an earthquake have been calculated for each zone. The results of this seismicity parameter provide useful information about the hazard level of a particular zone and further helps in preparing the hazard map of Northeast India.