The ladder sleeper, which is a type of longitudinal sleeper with long beams in the longitudinal direction of the rail, was developed for the maintenance-labor saving of ballast tracks. In this study, to quantify the load distribution performance of the ladder sleepers at the structural boundary, full-scale model tests were conducted to quantify the vibration transmission reduction effect of the ladder sleepers. Following that, numerical experiments were carried out using a three-dimensional numerical analysis model and it was revealed that the ladder sleeper can reduce the pressure on the sleeper bottom plane by approximately 70% when compared to conventional prestressed concrete sleepers. Furthermore, when laying the ladder sleeper at the structural boundary, it was shown that laying across the structural boundary may be more effective in reducing the pressure on the sleeper bottom plane than laying it in front of the structural boundary. Finally, ladder sleepers were installed on the commercial line and long-term measurements of the longitudinal level irregularity verified the effect of suppressing the longitudinal level irregularity of the ballasted ladder track.