2024
DOI: 10.1111/cts.13772
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Estimation of the benefit from pre‐emptive genotyping based on the nationwide cohort data in South Korea

Ki Young Huh,
Sejung Hwang,
Joo Young Na
et al.

Abstract: Genetic variants affect drug responses, making pre‐emptive genotyping crucial for averting serious adverse events (SAEs) and treatment failure. However, assessing the benefits of pre‐emptive genotyping based on genetic distribution, drug exposure, and demographics is challenging. This study aimed to estimate the population‐level benefits of pre‐emptive genotyping in the Korean population using nationwide cohort data. We reviewed actionable gene‐drug combinations recommended by both the Clinical Pharmacogenomic… Show more

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