Arthroplasty is commonly performed to treat advanced osteoarthritis or other degenerative joint conditions; however, it can also be considered for young patients with severe joint damage that significantly limits their functionality and quality of life. Young patients are still at risk of aseptic mobilization and bone resorption due to the phenomenon of stress shielding that causes an uneven distribution of tensions along the femoral contact surface prosthesis. This phenomenon can be limited by choosing the material of the prosthesis appropriately or by varying its stiffness, making sure that its mechanical behavior simulates that of the femur as much as possible. The aim of this study is to evaluate the mechanical strength of a prosthesis optimized both in shape and material and compare the results with a standard titanium prosthesis. Methods: Through three-dimensional modeling and the use of finite element method (FEM) software such as ANSYS, the mechanical behavior of traditional prosthesis and prosthesis optimized topologically respecting the ASTM F2996-13 standard. Results: With topological optimization, there is a stress reduction from 987 MPa to 810 MPa with a mass reduction of 30%. When carbon fiber is used, it is possible to further reduce stress to 509 MPa. Conclusions: The reduction in stress on the femoral stem allows an optimal distribution of the load on the cortical bone, thus decreasing the problem of stress shielding.