Estimation of total phenolic content, in–vitro antioxidant and anti–inflammatory activity of flowers of Moringa oleifera

Alhakmani, Fatma; Kumar, Santosh; Khan, Shah Alam

doi:10.1016/s2221-1691(13)60126-4

Cited by 309 publications

(188 citation statements)

References 16 publications

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“…It is commonly known as a horse-radish or drumstick tree in English and used as traditional medicine and livestock feed in many tropical and subtropical countries. Advantageously, it is a rapidly growing drought-resistant-deciduous tree even in poor soils ( Fuglie, 2001;Alhakman, Kumar, & Khan, 2013).…”

Section: Introductionmentioning

confidence: 99%

Comparative Proximate and Mineral Composition of Moringa oleifera and Moringa ovalifolia Grown in Central Namibia

Korsor¹,

Ntahonshikira²,

Bello³

et al. 2017

SAR

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The objective of this study was to compare the proximate and mineral compositions of Moringa oleifera and Moringa ovalifolia grown together at Neudamm Experimental Farm in central Namibia. Moringa oleifera is well known for its rich nutritional value and was compared to the nutritional value of M. ovalifolia, a native plant of Namibia and Angola, which is less studied. Namibia being a semi-arid country, many plants in the rangelands are low in nutrients essential for livestock nutrition. This creates the necessity for planting fodder trees like moringa that withstand the harsh climatic conditions and retain their nutritional quality for the production of sustained livestock supplement. Leaves of both Moringa species were harvested with twiglets, shade dried fortnightly and taken to the laboratory where they were ground and passed through 1 mm sieve for proximate and mineral analysis. Statistically, M. oleifera nutrient values were significantly different (P < 0.05) in moisture, ash, crude protein (CP) and crude fiber (CF) from M. ovalifolia, but had no differences in fat, acid detergent fiber (ADF) and neutral detergent fiber (NDF). Also, M. oleifera was significantly different (P < 0.05) from M. ovalifolia in potassium (K), magnesium (Mg), copper (Cu) and zinc (Zn), but there were no differences in calcium (Ca), sodium (Na), phosphorus (P), iron (Fe) and manganese (Mn) values. This implies that both Moringa species have similar quantity of Ca, Na, P, Fe and Mn in their leaf tissues. The almost identical nutrient values of the two Moringa species, suggests that M. ovalifolia could serve as an alternative supplement for livestock since there is a known human-livestock competition for M. oleifera, and since M. ovalifolia is native and well adapted to the harsh environmental conditions of Namibia.

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Section: Introductionmentioning

confidence: 99%

Comparative Proximate and Mineral Composition of Moringa oleifera and Moringa ovalifolia Grown in Central Namibia

Korsor¹,

Ntahonshikira²,

Bello³

et al. 2017

SAR

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“…The leaves of this species have a high content of vitamins, provitamins and minerals [33]. The pharmacological activities of M. oleifera may be due to various secondary plant metabolites present in M. oleifera such as flavonoids, phenolics, vitamins, carotenoids, minerals, sterols, amino acids, alkaloids, and glycosides [34]. M. oleifera leaves contains phenolic acids such as quinic acid and chlorogenic acid that exhibit high antioxidant activities [35,36] and recently β-sitosterol, was isolated from Moringa leaves fraction [37].…”

Section: Discussionmentioning

confidence: 99%

Healing Effect of Moringa oleifera Lam against UV-B Induced Psoriasis form Changes in Rats

Dilawar¹,

Shah²,

Hussain³

et al. 2017

Biochem Pharmacol (Los Angel)

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Moringa oleifera extracts have been used in herbal medicines by various communities in different parts of the world. It is a multipurpose tree with a magnificent profile of medicinal uses, high nutritional values and pharmacological activities. Various parts of this plant such as the flower, seed, immature pod, stem bark, leaf and root, possesses anti-oxidant, anticancer, antimicrobial, anti-ulcer, anti-hepatotoxic, antihypertensive, antihyperlipidemia, antidiabetic, antispasmodic, antiepileptic, antipyretic, anti-inflammatory and analgesic properties. An attempt was made to evaluate the healing properties of the methanolic extract of different aerial parts of Ultraviolet light-B was used to induce psoriasisform changes in rats. Irradiated rats were divided into 8 groups (6 rats/groups). The first group left untreated served as a control were given normal lab feed and a second group which served as the standard was administered retinoic acid (0.5 mg/kg) orally. Group III to Group VIII were administered orally with the methanolic extracts from aerial parts of M. oleifera (200 mg/kg bw) and (400 mg/kg bw). Data collected in this study was analyzed using statistical package for social sciences (SPSS) version 16. There was a significant difference (P<0.05) in epidermal thickness of control and drugs treated group. The methanolic extracts from aerial parts of M. oleifera used for treatment, enhanced fibroplasia, reduced inflammation and produced high amounts of scar tissue and enhanced the rate of wound healing and re-epithelisation compared to control. The plant extracts were effective against psoriasiform changes in rats. Though, more studies are required to assess which of its known ingredients are responsible for the antipsoriatic effects. The constituents of M. oleifera should be considered for further studies.

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“…Anti-inflammatory activity of samples was evaluated by protein denaturation method as described by Alhakmani et al, 23 . Diclofenac sodium (powerful non steroidal anti-inflammatory drug) was used as a standard drug.…”

Section: In-vitro Anti-inflammatory Activitymentioning

confidence: 99%

Effects of Physical and Chemical Modification on Biological Activities of Chitosan/ Carboxymethylcelluse Based Hydrogels

Benghanem

Chetouani

Elkolli

et al. 2017

J. Chil. Chem. Soc.

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Hydrogels network based on carboxymethylcellulose (CMC) and chitosan (CS), CC1 and CC2, have been prepared respectively in the presence or without the crosslinking agents [(N-hydroxysuccinimide (NHS)/N,N'-dicyclohexylcarbodiimide (DCC)] and characterized by FT-IR.The swelling behavior in distilled water at 25°C and biological activities have been investigated. CC1 hydrogel revealed higher potential swelling than CC2. Hydrogels showed to possess an important antioxidant activity equal to 66.67% for CC1 and 57.27% for CC2, to scavenge hydroxyl radicals at 2mg/mL. And the values of their reducing power were approximately 53% and 57%.From the hemolytic potential test the obtained materials were hemo-compatible. The anti-inflammatory activity exhibited that hydrogels were able to protect albumin from denaturation.

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Estimation of total phenolic content, in–vitro antioxidant and anti–inflammatory activity of flowers of Moringa oleifera

Cited by 309 publications

References 16 publications

Comparative Proximate and Mineral Composition of Moringa oleifera and Moringa ovalifolia Grown in Central Namibia

Comparative Proximate and Mineral Composition of Moringa oleifera and Moringa ovalifolia Grown in Central Namibia

Healing Effect of Moringa oleifera Lam against UV-B Induced Psoriasis form Changes in Rats

Effects of Physical and Chemical Modification on Biological Activities of Chitosan/ Carboxymethylcelluse Based Hydrogels

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