Estimation of trace and toxic metals in marine biota and associated health risk assessment in Thane Creek, Mumbai, India

Maity, Sukanta; Chaudhary, Dilip Kumar; Dusane, Chetan Kumar; Sahu, S. K.; Kumar, Amar

doi:10.1016/j.enceco.2021.07.002

Cited by 9 publications

(1 citation statement)

References 35 publications

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“…Zn level depends on the geological regions and pollution sources (air, soil, and rivers), with seawater salinity and pH affecting the relative proportion of different inorganic complexes with uncomplexed Zn 2+ , which is the most bioavailable form of Zn at the pH of seawater [6]. For example, among the marine organisms (crabs, prawns, and six different varieties of fish species) collected in an anthropic impacted area near Mumbai city (India), the highest concentration of Zn (31.2 mg/kg) was found in crabs [8]. Although from a geochemical point of view Li is a rare metal, nowadays many electronic devices in daily use require lithium-ion batteries, thus Li will increasingly be a key resource in the future [9].…”

Section: Introductionmentioning

confidence: 99%

Gene Expression Analysis of the Stress Response to Lithium, Nickel, and Zinc in Paracentrotus lividus Embryos

Bonaventura

Costa

Deidda

et al. 2022

Toxics

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Many anthropogenic pollutants such as metals are discharged into the marine environment through modern sources. Among these, lithium (Li), nickel (Ni), and zinc (Zn) can interfere with biological processes in many organisms when their concentration rises. These metals are toxic to sea urchin embryos, affecting their development. Indeed, animal/vegetal and dorso/ventral embryonic axes are differently perturbed: Li is a vegetalizing agent, Ni can disrupt dorso-ventral axis, Zn can be animalizing. To address the molecular response adopted by embryos to cope with these metals or involved in the gene networks regulating embryogenesis, and to detect new biomarkers for evaluating hazards in polluted environments in a well-known in vivo model, we applied a high-throughput screening approach to sea urchin embryos. After fertilization, Paracentrotus lividus embryos were exposed to Li, Ni, and Zn for 24/48 h. At both endpoints, RNAs were analyzed by NanoString nCounter technology. By in silico analyses, we selected a panel of 127 transcripts encoding for regulatory and structural proteins, ranked in categories: Apoptosis, Defense, Immune, Nervous, Development, and Biomineralization. The data analysis highlighted the dysregulation of many genes in a metal-dependent manner. A functional annotation analysis was performed by the KEEG Orthology database. This study provides a platform for research on metals biomarkers in sea urchins.

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Section: Introductionmentioning

confidence: 99%