Local knowledge can be a strategy for coping with extreme events and adapting to climate change. In Mexico, extreme events and climate change projections suggest the urgency of promoting local adaptation policies and strategies. This paper provides an assessment of adaptation actions based on the local knowledge of coffee farmers in southern Mexico. The strategies include collective and individual adaptation actions that farmers have established. To determine their viability and impacts, carbon stocks and fluxes in the system’s aboveground biomass were projected, along with water balance variables. Stored carbon contents are projected to increase by more than 90%, while maintaining agroforestry systems will also help serve to protect against extreme hydrological events. Finally, the integration of local knowledge into national climate change adaptation plans is discussed and suggested with a local focus. We conclude that local knowledge can be successful in conserving agroecological coffee production systems.