The recent COVID 19 pandemic has brought with it a different way of living for all humanity, in this situation the way we communicate, socialize, shop and work among many other activities has changed considerably. The main objective of this research is to detect whether psychological problems such as: anxiety, depression, stress, exhaustion, and low concentration are factors that influence work and school deterioration in people who carry out activities ON-LINE. The investigation was realized in the municipality of Nezahualcóyotl during confinement at home due to the COVID-19 pandemic. The research results highlight that the main psychological problems presented by students and employees is "exhaustion" (27%), followed by "low concentration" (26%) and "stress" (18%). More than half of the interviewees consider that the origin of these psychological problems are workloads and tasks; While 11% say it is due to the situation of the pandemic and in the presence of these problems, 89% say that they have caused the deterioration of their activities.