Estuary is an exclusive system and have an important role but also have vulnerabilities that can threaten life in the estuary region, so it is necessary to have knowledge of estuarine boundaries so that conservation can be maintained. This study aims to analyze the boundaries of the Cimandiri Estuary and the Cisadane Estuary based on surface water salinity, and analyze the relationship of estuarine surface water salinity with rainfall, sea surface currents and tides in the Cimandiri Estuary and Cisadane Estuary. The variables used in this study are salinity, rainfall, sea surface currents, and tides. The research method use the Cimandiri Algorithm by processing OLI Landsat 8 Imagery in 2018 and 2019. The results of this study are estuary boundaries divided into 3 estuary boundary classes specifically Mexo-oligohaline (0.5-5 ‰), Mexo-mesohaline (5-18 ‰), and Mexo-polyhaline (18-30 ‰). Cimandiri’s salinity value is strongly affected by season, then by tides and last by the currents, it is because the Cimandiri Estuary has a deep waters. Meanwhile in the Cisadane Estuary, the salinity value is strongly influenced by season, then by the currents and tides, and also influenced by freshwater from land, it is because the Cisadane Estuary has a shallow water.