Teotihuacan was an important city in Mesoamerica and during the first centuries AD was the most important city in the Center of Mexico. It has been investigated during several years by different projects, but there is still much work to do. The goal of the project is to understand the organization of a neighborhood located in an area in the center of Teotihuacan, between San Juan River, the Pyramid of the Sun and the Street of the Dead, named by Millon "sectors N2E1 and N2E2", through the combined application of different research techniques. We applied aerial photography with drone, topography, geophysical prospection techniques (magnetic, electric and georadar studies) to identify buried structures and the study of chemical residues on the soil surface and the distribution of archaeological materials in selected areas, to identify human activities. The data obtained until now, suggest preliminary hypotheses about the distribution and depth of buried buildings, that should be part of a neighborhood with its components such as residential areas, workshops, temples, and squares. I.