“…The pulsatility index reflects the distal vascular resistance to the middle cerebral artery, and this is in relation to small‐vessel disease (16) and has been associated with the development of leukoaraiosis (33). Previous studies have linked the elevation in the pulsatility index to the presence of small‐vessel disease determined in MRI as peri ventricular and deep white matter hyperintensities and lacunar infarcts, with 89% sensitivity and 86% specificity (34), especially in diabetic patients (35).…”
The association of retinal microangiopathy (but not vascular retinopathy) and leukoaraiosis is linked to small-vessel disease and may be a useful marker of lacunar infarcts not secondary to a macrovascular lesion.
“…The pulsatility index reflects the distal vascular resistance to the middle cerebral artery, and this is in relation to small‐vessel disease (16) and has been associated with the development of leukoaraiosis (33). Previous studies have linked the elevation in the pulsatility index to the presence of small‐vessel disease determined in MRI as peri ventricular and deep white matter hyperintensities and lacunar infarcts, with 89% sensitivity and 86% specificity (34), especially in diabetic patients (35).…”
The association of retinal microangiopathy (but not vascular retinopathy) and leukoaraiosis is linked to small-vessel disease and may be a useful marker of lacunar infarcts not secondary to a macrovascular lesion.
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