The object of this research is the postcolonial theory, while the subject is its impact upon the historical, and namely, historical-anthropological research of Latin America. The author examines such peculiarities of post-colonialism as the problem of identification, the “oppressed”, the importance of linguistic component of scientific description, as well as the political bias of this direction. Attention is turned to the process of adaptation of postcolonial theory to Latin American scientific foundation; emphasis is placed on the fact that the region has its own tradition of interpretation of the colonial past that results in occurrence of the so-called phenomenon of decolonial turn within the Latin American humanities. Based on the comparative method and qualitative content analysis of the works dedicated to postcolonial theory, the author demonstrates the presence of a wide range of opinions of Latin American researchers on such concepts as “colonialism: and “Latin Americanism”. The conclusion is made that the intense discussion on the theoretical aspects of colonial and decolonial theory may underlie the new vector in the historical studies of Latin America. At the same time, decolonial turn alongside postcolonial theory, raise a number of questions, the solution of which is vital for the development of accurate methodology for further scientific research. For the Russian Latin American scholars, the new trends turn into a special challenge that should be considered in carrying out historical and anthropological research.