Estudo da camada de fibras nervosas da retina em pacientes com esquistossomose mansônica: análise com GDxTM

Histological and histomorphometric evaluation of the retina of mice infected with Schistosoma mansoni in its hepatosplenic form

“…The fact that the object of study was the peripapillary region may have influenced the lack of ocular findings, as already described in other studies [4][5][6][7][8][9][10][11][12][13][14][15][16][17] . It was not searched throughout the globe since the intention was to evaluate a particular segment of the eye.…”

“…Ocular lesions have been reported with an inflammatory response induced by S. mansoni eggs similar to those observed in the livers of infected hosts. Retinal manifestations, such as hemorrhages, granulomas, tortuosity and enlargement of the vessels were observed in association with the hepatosplenic form [4][5][6][7][8][9][10][11][12][13][14][15][16][17] . Damage to the retinal nerve fiber layer and the retard of retinal contrast arrival time in the angiofluoresceinographic exam were also reported due to ocular hemodynamic alterations 6,8,11 .…”