Estudo da correlação entre molusco contagioso e dermatite atópica em crianças

Seize, Maria Bandeira de Melo Paiva; Ianhez, Mayra; Cestari, Silmara da Costa Pereira

doi:10.1590/s0365-05962011000400006

Cited by 30 publications

(14 citation statements)

References 23 publications

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“…One clinical review of 284 children noted more lesions and a greater extent of surrounding eczema in patients presenting with MC and AD compared to those patients presenting with MC alone [11]. Indeed, there are indications that AD may be a risk factor for acquisition of MCV and that patients with AD may suffer a more extensive course of MC illness [12], but, to date, there are no case-control studies to evaluate these hypotheses.…”

Section: Introductionmentioning

confidence: 99%

Molluscum Contagiosum in a Pediatric American Indian Population: Incidence and Risk Factors

et al. 2014

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BackgroundMolluscum contagiosum virus (MCV) causes an innocuous yet persistent skin infection in immunocompetent individuals and is spread by contact with lesions. Studies point to atopic dermatitis (AD) as a risk factor for MCV infection; however, there are no longitudinal studies that have evaluated this hypothesis.MethodsOutpatient visit data from fiscal years 2001–2009 for American Indian and Alaska Native (AI/AN) children were examined to describe the incidence of molluscum contagiosum (MC). We conducted a case-control study of patients <5 years old at an Indian Health Service (IHS) clinic to evaluate dermatological risk factors for infection.ResultsThe incidence rate for MC in children <5 years old was highest in the West and East regions. MC cases were more likely to have a prior or co-occurring diagnosis of eczema, eczema or dermatitis, impetigo, and scabies (p<0.05) compared to controls; 51.4% of MC cases had a prior or co-occurring diagnosis of eczema or dermatitis.ConclusionsThe present study is the first demonstration of an association between AD and MC using a case-control study design. It is unknown if the concurrent high incidence of eczema and MC is related, and this association deserves further investigation.

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Section: Introductionmentioning

confidence: 99%

Molluscum Contagiosum in a Pediatric American Indian Population: Incidence and Risk Factors

et al. 2014

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“…Значительное снижение качества жизни пациентов, множественная коморбидность, социальные аспекты заболевания предопределяют интерес к дальнейшему изучению эпидемиологических проблем [2,4,5,[22][23][24][25][26][27][28][29][30][31][32][33][34].…”

Section: Discussionunclassified

“…Серьезно осложнить течение атопического дерматита может инфекция, обусловленная вирусом Коксаки [31]. Некоторые авторы [32][33][34][35] риск развития атопического дерматита у ребенка [36]. Такой же эффект оказывает активное курение матери в первые годы жизни ребенка и пассивное курение ребенка [37,38].…”

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Epidemiology of atopic dermatitis

Хамаганова¹,

Новожилова²,

Vorontsova³

2017

Klin. dermatol. venerol.

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В настоящее время не вызывает сомнений генетическая предрасположенность к аллергическим заболеваниям, выявляемая в разных странах [1-3]. Это предопределяет повсеместное распространение и рост заболеваемости атопическим дерматитом. Проявления заболевания существенно снижают качество жизни пациентов, приводят к продолжительным периодам нетрудоспособности [4]. В частности, течение атопического дерматита во многих случаях связано с расстройствами сна [5].

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“…However, the prevalence may be underestimated because many studies have focused on MC-affected children who visited a medical clinic, and, therefore, have failed to include MC patients who did not seek medical treatment. 8 Risk factors for MC include swimming, 9,10 affected siblings, 4,11 atopic dermatitis (AD), 3,[11][12][13][14][15][16][17] and filaggrin (FLG) gene mutations. 18 Swimming and siblings living together can facilitate transmission of the virus by direct contact with infected persons and fomites.…”

Section: Introductionmentioning

confidence: 99%

Association between filaggrin gene mutations and the clinical features of molluscum contagiosum: The Yamanashi Adjunct Study of the Japan Environment and Children's Study

Kojima,

Miyake,

Shinohara

et al. 2024

The Journal of Dermatology

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Previous studies have reported swimming, atopic dermatitis, and filaggrin (FLG) gene mutations as risk factors for molluscum contagiosum (MC) infection. FLG gene mutations impair skin barrier function. The aim of this study was to determine the impact of FLG mutations on the incidence and clinical features of MC. We used data from 2036 children who participated in the Yamanashi Adjunct Study of the Japan Environment and Children's Study, a prospective, birth cohort study. A questionnaire for caregivers (when children were 4 and 8 years of age) asked about clinical features including previous MC incidence and treatment, number of MC lesions at first visit, and time to resolution. Participants underwent genotyping to detect six FLG mutations that are common in the Japanese population. A logistic regression model was used to analyze the association between MC incidence and FLG mutations, adjusted for potential confounders. The cumulative incidence of MC at age 8 years was 47.1%. Among participants with a history of MC, 67.6% had undergone curettage. FLG mutation was a significant risk factor for MC incidence (adjusted odds ratio [aOR] 1.69, 95% confidence interval [CI] 1.18–2.42). Swimming and atopic dermatitis were also significant risk factors for MC. There was no significant association between FLG mutation and the number of MC lesions at the first visit or the time to resolution of lesions. FLG mutation is a risk factor for MC incidence; however, FLG mutations do not affect the number of MC lesions at presentation or the time to resolution.

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Estudo da correlação entre molusco contagioso e dermatite atópica em crianças

Cited by 30 publications

References 23 publications

Molluscum Contagiosum in a Pediatric American Indian Population: Incidence and Risk Factors

Molluscum Contagiosum in a Pediatric American Indian Population: Incidence and Risk Factors

Epidemiology of atopic dermatitis

Association between filaggrin gene mutations and the clinical features of molluscum contagiosum: The Yamanashi Adjunct Study of the Japan Environment and Children's Study

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