Estudo do remodelamento ventricular e dos anéis valvares na cardiomiopatia dilatada: avaliação anátomo-histopatológica

Dalva, Moise

doi:10.11606/t.5.2012.tde-05042012-085911

Cited by 1 publication

(1 citation statement)

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“…However, few studies have evaluated the ventricular chambers splitting them into segments, or observing the changes in size in different places inside the chambers, thus seeking for understanding the real complexity of the geometrical changes in the ill heart. These can give support to the deepening of studies about the influence of the geometrical deformation on cardiac performance as well as the development of more accurate techniques to provide a reverse remodeling [ 6 - 8 ] .…”

Section: Introductionmentioning

confidence: 99%

Idiopathic Dilated Cardiomyopathy: computerized anatomic study of relashionship among septal and free left ventricle wall

Juliani¹,

Costa²,

Correia³

et al. 2014

Revista Brasileira De Cirurgia Cardiovascular

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Introduction A feature of dilated cardiomyopathy is the deformation of ventricular cavity, which contributes to systolic dysfunction. Few studies have evaluated this deformation bearing in mind ventricular regions and segments of the ventricle, which could reveal important details of the remodeling process, supporting a better understanding of its role in functional impairment and the development of new therapeutic strategies. Objective To evaluate if, in basal, equatorial and apical regions, increased internal transverse perimeter of left ventricle in idiopathic dilated cardiomyopathy occurs proportionally between the septal and non-septal segment. Methods We performed an anatomical study with 28 adult hearts from human cadavers. One group consisted of 18 hearts with idiopathic dilated cardiomyopathy and another group with 10 normal hearts. After lamination and left ventricle digital image capture, in three different regions (base, equator and apex), the transversal internal perimeter of left ventricle was divided into two segments: septal and not septal. These segments were measured by proper software. It was established an index of proportionality between these segments, called septal and non-septal segment index. Then we determined whether this index was the same in both groups. Results Among patients with normal hearts and idiopathic dilated cardiomyopathy, the index of proportionality between the two segments (septal and non-septal) showed no significant difference in the three regions analyzed. The comparison results of the indices NSS/SS among normal and enlarged hearts were respectively: in base 1.99 versus 1.86 (P=0.46), in equator 2.22 versus 2.18 (P=0.79) and in apex 2.96 versus 3.56 (P=0.11). Conclusion In the idiopathic dilated cardiomyopathy, the transversal dilatation of left ventricular internal perimeter occurs proportionally between the segments corresponding to the septum and free wall at the basal, equatorial and apical regions of this chamber.

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Section: Introductionmentioning

confidence: 99%