Estudo morfométrico da terapia LED de baixa potência em tendinite de ratos

Silva, José Mário Nunes da; Carvalho, Janderson Pereira de; Júnior, Manoel de Jesus Moura

doi:10.1590/s1809-29502011000400012

Cited by 5 publications

(6 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Casalechi et al [23] performed a study that aimed to evaluate the effects of therapy LED on the process of tissue repair in rats submitted to experimental traumatic process of tendinopathy; a significant reduction in the number of fibroblasts was evidenced; after irradiation with the therapy LED, findings that reinforce the results were obtained by Parente et al [13]; they concluded in their study that the therapy LED propitiated beneficial effects on the reduction in the number of inflammatory cells and the alignment of collagen fibers, which corroborates with the findings of Silva; Carvalho and Moura-Junior [25] observed effects PBM after irradiation with a dose equal to 4 J/cm 2 , favoring a higher proinflammatory action.…”

Section: Discussionsupporting

confidence: 84%

Effects of Therapy with Light Emitting Diode (LED) in the Calcaneal Tendon Lesions of Rats: A Literature Review

Nascimento

Pessoa

et al. 2019

The Scientific World Journal

View full text Add to dashboard Cite

The objective of this review was to analyze original articles about the effects of therapy with LED in experimental models of calcaneal tendon lesions of rats. The search was performed in the period from February to May 2018, in the following electronic databases: MEDLINE, SciELO, and LILACS, besides the Google Scholar, using the descriptors “Achilles tendon”, “Rats”, “LED”, “Tendinopathy”, and “Low-level Light Therapy”, as well as their matching parts in the Portuguese and Spanish languages, related to and in association with the relevant terms to the content sought. From the descriptors used 215 works were found. After application of eligibility criteria 8 works were selected, in which positive results were found after the application of the LED. Regarding the main results found with phototherapy, we observed a significant reduction in inflammation. Only one article mentioned little reduction of inflammation. In relation to the number of sessions, there was wide variation, with an average of approximately 5 sessions every 24 hours. Studies in this review pointed out, therefore, positive results in the repair of the calcaneal tendon after therapy with irradiation LED; however, carrying out more experimental studies that help the standardization of parameters to be used in this therapy for further clinical studies becomes necessary.

show abstract

Section: Discussionsupporting

confidence: 84%

Effects of Therapy with Light Emitting Diode (LED) in the Calcaneal Tendon Lesions of Rats: A Literature Review

Nascimento

Pessoa

et al. 2019

The Scientific World Journal

View full text Add to dashboard Cite

show abstract

“…Dentre os efeitos da fototerapia nos tecidos biológicos, um dos mais discutidos é sua influência sobre os fibroblastos, na síntese de colágeno, no remodelamento e na melhora funcional dos tendões 14 . Alguns estudos demonstram que há aumento do número de fibroblastos em tecidos tratados com essa terapia 15,16 .…”

Section: Discussionunclassified

“…As fibras colágenas no grupo LED apresentou melhor remodelamento em relação aos demais grupos que sofreram lesão. Esses resultados corroboram os de outros trabalhos em que se utilizou a fototerapia, como apresentado na literatura 2,11,12,14,15,20 .…”

Section: Revisão De Literaturaunclassified

Análise do efeito da LED (light emitting diode) terapia em tendinopatia traumática em ratos

Parente¹,

Vieira

Casalechi

et al. 2013

Cons. Saúde

View full text Add to dashboard Cite

Introdução: A tendinopatia refere-se a qualquer processo mórbido e/ou doença que afeta os tendões (tendinite e/ou tendinose). Objetivo: Investigar o efeito da fototerapia (LED 640 nm) no processo de reparação da tendinite no tendão calcâneo de rato. Método: A tendinite foi induzida no tendão calcâneo esquerdo por meio de trauma mecânico. Foram utilizados 40 ratos Wistar (300 ± 20g), divididos em quatro grupos com dez animais, cada grupo foi subdividido em dois subgrupos com cinco roedores para os tempos experimentais de 7 e 21 dias. Os grupos foram nomeados da seguinte forma: CONTR, TEND, LED, DROG. Para análises histopatológicas foi determinado p≤0,05. Resultados: Houve menor número de células inflamatórias e maior reparação tecidual nos grupos tratados com LED. Conclusão: Com os resultados obtidos, concluiu-se que o LED de baixa potência tem ação positiva no processo anti-inflamatório e na reparação em tendão calcâneo de ratos.

show abstract

“…During laser application, the animals were immobilized manually and positioned in ventral decubitus, according to the protocol used by Xavier et al (2010). The device was positioned perpendicularly to the injury, and the radiation was always performed at the same time of the day, with 24h intervals between applications, as proposed by Taciro et al (2007) and Silva et al (2011). As a security measure, the professionals used laser goggles (Ibramed Indústria Brasileira de Equipamentos Médicos Ltda, Amparo, SP, Brazil) for protection against radiation.…”

Section: Methodsmentioning

confidence: 99%

Histomorphometric analysis of the Achilles tendon of Wistar rats treated with laser therapy and eccentric exercise

Souza

Moreira²,

Silva³

et al. 2015

Pesq. Vet. Bras.

View full text Add to dashboard Cite

Low-level laser therapy is recommended for the treatment of tendinopathies despite the contradictory results related to the ideal dose of energy, wavelength and time of application. This study aimed to assess the effects of laser therapy and eccentric exercise on tendinopathy of the Achilles tendon of Wistar rats. Forty-eight adult male rats were randomly distributed into four groups (L= laser; E= eccentric exercise; LE = laser and eccentric exercise; and R= rest). Laser therapy (904nm/3J/cm²) and/or eccentric exercise (downhill walking; 15 o incline treadmill; 12m/min; 50min/day) was started 24h after induction of unilateral tendinopathy and remained for 20 days. At 3, 7, 14 and 21 days after lesion induction, three rats from each group were euthanized and the tendons were collected for histological and morphometric analyses. There was no difference among groups or among times for the characteristics hemorrhage (p=0.4154), fibrinous adhesion formation (p=0.0712), and organization of collagen fibers (p=0.2583) and of the connective tissue (p=0.1046). For these groups, regardless of the time, eccentric exercise led to epitenon thickening (p=0.0204), which was lower in the group treated with laser therapy. Histological analysis revealed differences (p=0.0032) in the number of inflammatory cells over time. They were more numerous in the group that only exercised. This result was confirmed by morphometric analysis, which showed a significant interaction (groups x time) for this characteristic. Eccentric exercise increased (p=0.0014) the inflammatory infiltrate over time (3 and 21 days). However, association with laser therapy reduced inflammatory reaction. On the other hand, the combination of the treatments increased angiogenesis in morphometric (p=0.0000) and histological (p=0.0006) analyses compared with the other groups, while the isolated application of low-level laser reduced this characteristic over time. Animals maintained at rest presented the lowest amount (p=0.0000) of fibroblasts, according to the morphometric analysis. However, histological evaluation showed a significant group x time interaction (p=0.0024). Greater amounts of fibroblasts were observed in groups E, L and LE on the 7 th , 14 th and 21 st days, respectively. The animals that received laser therapy and were exercised showed a greater (p=0.0000) amount of collagen fibers over time. LE=laser e exercício excêntrico, e R=repouso). Após 24h da indução de tendinopatia unilateral, foi iniciada laserterapia (904nm/3J/cm²) e/ou exercício excêntrico (caminhada em declive; esteira com 15 o de inclinação; 12m/min; 50min/ dia) que permaneceu por 20 dias. Aos 3, 7, 14 e 21 dias após indução da lesão, três ratos de cada grupo foram submetidos à eutanásia, e os tendões foram obtidos para análi-ses histológica e morfométrica. Não houve diferença entre grupos nem entre tempos nas características hemorragia (p=0,4154), formação de aderência fibrinosa (p=0,0712) e organização das fibras colágenas (p=0,2583) e do tecido conjuntivo (p=0,1046). Considerando os g...

show abstract

Estudo morfométrico da terapia LED de baixa potência em tendinite de ratos

Cited by 5 publications

References 18 publications

Effects of Therapy with Light Emitting Diode (LED) in the Calcaneal Tendon Lesions of Rats: A Literature Review

Effects of Therapy with Light Emitting Diode (LED) in the Calcaneal Tendon Lesions of Rats: A Literature Review

Análise do efeito da LED (light emitting diode) terapia em tendinopatia traumática em ratos

Histomorphometric analysis of the Achilles tendon of Wistar rats treated with laser therapy and eccentric exercise

Contact Info

Product

Resources

About