2015
DOI: 10.1016/j.adengl.2015.01.003
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Etanercept Combined With Systemic Drugs or Phototherapy for Treatment of Psoriasis

Abstract: Biologic drugs have provided excellent results in the treatment of moderate to severe psoriasis. Nevertheless, in routine clinical practice, combinations of biologic drugs with phototherapy or systemic drugs can increase efficacy, diminish toxicity, and reduce the cost of treatment. Published experience with these combinations is scarce, although the results are often satisfactory. This review examines the most relevant published experience in the combination of the most studied drug in this field-etanercept-w… Show more

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“…Recent studies also suggest that down‐titration may be possible without compromising disease control . Furthermore, etanercept can also be used in combination therapy; the combination of etanercept plus MTX or acitretin has shown benefit in patients inadequately responding to monotherapy and UVB–etanercept combination treatment has proven to have a synergistic effect, although usage should be reserved for selected cases owing to potential carcinogenicity concerns …”
Section: Etanercept Overviewmentioning
confidence: 99%
“…Recent studies also suggest that down‐titration may be possible without compromising disease control . Furthermore, etanercept can also be used in combination therapy; the combination of etanercept plus MTX or acitretin has shown benefit in patients inadequately responding to monotherapy and UVB–etanercept combination treatment has proven to have a synergistic effect, although usage should be reserved for selected cases owing to potential carcinogenicity concerns …”
Section: Etanercept Overviewmentioning
confidence: 99%