integrated devices. The channels can be freely suspended, and top-side, bottom-side and in-plane fluidic interfacing is possible. Transducer structures can be integrated in close proximity to the fluid using suitable materials. In these microfluidic handling systems, many different microfluidic devices can be integrated on the same chip. As a result, these devices are connected with very small internal volumes which allows for fast response times and handling of small sample sizes. Several options are proposed to add functionality to the devices. Some examples of these are: metalization, release of the channels from the bulk or a buried oxide layer to mechanically or electrically isolate parts of the chip or provide buried fluidic channels.In this paper, we discuss several channel etching methods and look at their applicability in the platform. The full fabrication process is discussed in Groenesteijn et al. (2017). The channels are etched isotropically through etch slits in a silicon-rich silicon nitride layer on top of the wafer. As a result, the size and shape of the channels can be tuned to meet the demands of any application. Here, we propose a method, based on an empirical etch model, to design the slit pattern that will result in the desired channel shape.In Sect. 4, the channel design of an integrated microfluidic handling system with multiple fluidic sensors is discussed.
Fabrication outlineThe fabrication of the devices can be roughly divided into three main steps: fabrication of the microchannels, fabrication of the functional structures and fabrication of the fluidic access to the channels. In this section, an outline of the fabrication process is given where channels are etched at Abstract Microfluidic devices often require channels of a specific size and shape. These devices are then made in a fabrication process that is often specialized to produce only those (and very similar) channels. As a result, devices requiring channels of different size and shape cannot easily be integrated on the same chip. This paper presents a method to fabricate microfluidic channels in a wide range of shape and size on the same chip by using a slit pattern through which the channels are etched. The fabrication process to fabricate these channels is discussed in detail, and an empirical model is presented to find the optimal slit pattern for a required size and shape. This part of the paper focusses on the channel design and fabrication. Details on the whole fabrication process and optional functionalization of the channels are presented in part I of this paper.