Ethical Aspects of Banking Placental Blood for Transplantation

Sugarman, Jeremy; Reisner, Emily G.; Kurtzberg, Joanne

doi:10.1001/jama.1995.03530220049032

Cited by 52 publications

(22 citation statements)

References 9 publications

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“…UCB banking raises a series of important epistemic social and ethical concerns, including issues of ownership and consent, the imperatives of commercial banking, and donor privacy [1][2][3][4].…”

Section: Ethical Issues Raised By Ucb Bankingmentioning

confidence: 99%

“…This paper reviews the history of UCB banking, examines the scientific and clinical evidence that has provided the impetus for their establishment, and discusses the ethical issues raised by UCB banking. Although some of these issues have been debated in the North American and European context [1][2][3][4][5][6], there has been limited examination of these issues in Australia. This paper seeks to fill this gap.…”

Section: Introductionmentioning

confidence: 99%

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Equity, Utility, and the Marketplace: Emerging Ethical Issues of Umbilical Cord Blood Banking in Australia

Samuel

Kerridge

2007

Bioethical Inquiry

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Over the past decade, umbilical cord blood (UCB) has routinely been used as a source of haematopoietic stem cells for allogeneic stem cell transplants in the treatment of a range of malignant and non-malignant conditions affecting children and adults. UCB banks are a necessary part of the UCB transplant program, but their establishment has raised a number of important scientific, ethical and political issues. This paper examines the scientific and clinical evidence that has provided the basis for the establishment of UCB banks. We also discuss the major ethical issues that UCB banks raise, including ownership of cord blood, processes for obtaining consent for its collection and storage, and confidentiality. Finally, we review other concerns about commercial non-altruistic banking, including concerns about social justice, equity of access and equity of care.

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Section: Ethical Issues Raised By Ucb Bankingmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Equity, Utility, and the Marketplace: Emerging Ethical Issues of Umbilical Cord Blood Banking in Australia

Samuel

Kerridge

2007

Bioethical Inquiry

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“…Denn nur auf diese Weise besteht Aussicht auf eine ausreichende Versorgung mit passenden Blutkonserven zur Transplantation (vgl. [18] S. 1785; [17] S. 941 und [7], S. 1321). Die Frage nach der Entwicklung von Methoden, die eine gleichmäßige Gewinnung sowie eine faire Verteilung des Nabelschnurblutes garantieren, muss im Rahmen dieses Beitrags allerdings unbeantwortet bleiben.…”

Section: Die Fairnessunclassified

“…Im Unterschied zur Gewinnung von Stammzellen aus Nabelschnurblut belastet man den Spender sowohl bei der Gewinnung von 1 Bei der Verwendung der Stammzellen für Transplantationen wird unterschieden zwischen autologem und allogenem Gebrauch, d.h. zwischen der Verwendung des Transplantats bei einem Patienten, der gleichzeitig ebenfalls Donor ist, und jener, bei der Patient und Donor nicht identisch sind 2 Vgl. [4,13,14,16,18,19] Stammzellen mittels Apherese aus peripherem Blut als auch bei der Gewinnung von Stammzellen aus Knochenmark, wenngleich auf andere Art: Wo der Spender für die Gewinnung von Knochenmark narkotisiert werden muss, muss er für die Gewinnung von Stammzellen mittels Apherese aus peripherem Blutzwecks "Mobilisierung" der Stammzellen -mit Wachstumsfaktoren vorbehandelt werden, welche ihrerseits mit verschiedensten Nebenwirkungen behaftet sind. Der Spender geht bei der Gewinnung von Nabelschnurblut im Gegensatz zur Gewinnung von Knochenmark kein erhöhtes Krankheits-wenn nicht gar Sterberisiko ein.…”

Section: Introductionunclassified

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Ethische Fragen zur Stammzellentransplantation aus Nabelschnurblut

Gordijn

Olthuis²

2000

Ethik in der Medizin

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Ethical issues with regard to transplantation of cord blood stem cellsAbstract. Definition of the problem: Cord blood banks have been and are still being set up in many modern states all over the world. Cord blood transplantation, however, gives rise to a specific set of ethical problems, that must be cleared up and analyzed before full responsibility can be assumed and the establishment of banks for frozen cord blood samples and the structural implementation of cord blood transplantation can be justified. The main ethical issues concerning cord blood stem cell transplantation can be divided into at least six groups of questions that are closely related. First, there are ethical issues concerning the status of the treatment. Must cord blood transplantation somehow still be considered an "investigational" treatment or can it be regarded as accepted therapy? Second, we must face the question of the ownership of the placental tissue. Third, there are questions regarding the fairness in the collection and distribution of cord blood. Fourth, there is the issue of informed consent. Fifth, there is the question of whether how new data from medical testing will be communicated to the parents or the donor. Finally, questions related to privacy and confidentiality need to be addressed. Conclusion: As it is likely in the years to come that the supply and demand for cord blood will grow, clinicians will increasingly need answers to these ethical questions. Only thoughtful analysis of the attendant ethical issues of the establishment of banks for frozen blood samples and the structural implementation of cord blood transplantation can mitigate potential problems.

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Research and Stored Tissues

Knoppers¹

1995

JAMA

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Ethical Aspects of Banking Placental Blood for Transplantation

Cited by 52 publications

References 9 publications

Equity, Utility, and the Marketplace: Emerging Ethical Issues of Umbilical Cord Blood Banking in Australia

Equity, Utility, and the Marketplace: Emerging Ethical Issues of Umbilical Cord Blood Banking in Australia

Ethische Fragen zur Stammzellentransplantation aus Nabelschnurblut

Research and Stored Tissues

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