Background. Surveys indicate considerable variation regarding the provision of cancer treatment at the end of life. The variation cannot be fully explained by differences concerning the clinical situation or patients' preferences. The aim of this qualitative study was to explore medical oncologists' experiences with advanced cancer, as well as their views of the relevance of medical and nonmedical criteria for decisions about limiting treatment.Methods. Qualitative in-depth interviews were conducted with physicians working in medical oncology in tertiary care hospitals or district general hospitals in England. Purposive sampling and qualitative analysis were performed. Implications for Practice: Survey research indicates that there is considerable variation concerning treatment at the end of life that cannot be explained by clinical features or patients' individual preferences. This qualitative study adds to existing literature by providing information about physicians' distinctions (i.e., "active treatment" versus "palliative care") and related clinical as well as ethical implications in the context of care for patients with advanced cancer. In addition, the interviewed oncologists report a number of value-laden non-medical factors that are viewed as influential for decisions about the provision or limitation of cancer treatment against the background of often scarce evidence. The findings of this study suggest that, in clinical practice, multi-professional team discussions on value aspects of decision making and a systematic gathering and analysis of clinical data that can be applied to end-of-life practice may contribute to an improved evidence-and ethics-based treatment decision making in advanced cancer.
Results. Physicians reported that a number of nonmedical