This chapter explores innovative quality management approaches in public healthcare systems, focusing on transitioning from traditional protocols to modern, data-driven strategies. The authors examine digital health solutions' effectiveness and implementation challenges, process improvement methodologies, and collaborative care models. Through a comprehensive literature review and analysis of recent trends, the chapter identifies key barriers and facilitators influencing the adoption of these innovative approaches. The research highlights the impact of these strategies on clinical outcomes, operational efficiency, and patient experience. A framework for quality management in public healthcare is proposed, integrating innovative approaches with implementation factors. The chapter concludes by offering recommendations for healthcare practitioners, policymakers, and researchers to enhance quality management practices and outlines future research directions in this rapidly evolving field.