Ethical issues and public communication in the development of cell-based treatments for COVID-19: Lessons from the pandemic

Turner, Leigh; Munsie, Megan; Levine, Aaron; Ikonomou, Laertis

doi:10.1016/j.stemcr.2021.09.005

Cited by 12 publications

(8 citation statements)

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“…In addition, many clinics worldwide administer unproven stem cell therapies to patients with devastating diseases, often in the absence of any scientific rationale ( 22 ). This was highlighted in the recent years when the COVID-19 pandemic has increased the proposal of self-proclaimed treatments including more appealing stem cells-like based approaches ( 23 , 24 ). Indeed, the advertisement of commercial entities of unproven therapies on their websites is especially cheeky.…”

Section: The Landscapes For New Atmp Developmentmentioning

confidence: 99%

Education for the translation of Advanced Therapy Medicinal Products

2023

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Section: The Landscapes For New Atmp Developmentmentioning

confidence: 99%

Education for the translation of Advanced Therapy Medicinal Products

2023

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“…The COVID-19 pandemic has raised important ethical issues at various levels, such as respect for quarantine rules and sacrifice for the common good; saving the economy or human life (choosing patients for the first time for treatment); continuing working activities, and endangering the health of loved ones; deciding to return to one's hometown at risk of an outbreak, especially during a pandemic [22,23]. Because ethical problems and ethical distress are often inevitable [22], an ethical dilemma is a problematic situation involving a conflict between two unique reciprocal options, showing both negative and undesirable consequences [24][25][26].…”

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confidence: 99%

“…The COVID-19-pandemic has brought many ethical issues into a new, urgent light. A significant body of literature is available on ethical concerns in pandemics and a variety of severe ethical problems throughout the pandemic [23]. This is a situation in which a person is confronted with two ethical principles, as opposed to each other, which involve maximizing the public interest based on a benefit analysis or deciding on unconditional respect for the law, regardless of the consequences.…”

Section: Of 24mentioning

confidence: 99%

“…This is a situation in which a person is confronted with two ethical principles, as opposed to each other, which involve maximizing the public interest based on a benefit analysis or deciding on unconditional respect for the law, regardless of the consequences. Ethical distress occurs when individuals know which option is ethically appropriate but cannot choose due to internal or external constraints [23,27,28]. In emergencies such as pandemics, some decisions are made under stress, and several studies have shown that stress can affect ethical decision making [29][30][31][32][33].…”

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confidence: 99%

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The Relationship between Prevention and Panic from COVID-19, Ethical Principles, Life Expectancy, Anxiety, Depression and Stress

Salehi

Zimon

Ghaderi

et al. 2022

IJERPH

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The present study aims to assess the relationship between prevention and panic from COVID-19, ethical principles, life expectancy, anxiety, depression, and stress in auditors and financial managers of small- and medium-sized Iraqi firms. In other words, this paper seeks to answer the question of whether different types of prevention and panic from COVID-19 can enhance the ethical principles, life expectancy, anxiety, depression, and stress, or not. The study method is practical in its objective and descriptive survey procedure. The study’s statistical population includes 185 employed auditors in audit firms, and 215 financial managers of small- and medium-sized Iraqi firms were selected as a sample of the study using the Cochran Sampling Method. In this paper, PLS tests are used to assess the effect of independent variables on the dependent variable. The results indicate no significant relationship between prevention from COVID-19 and ethical principles and life expectancy. However, the association between prevention from COVID-19 and anxiety, depression, and stress, and between panic from COVID-19 and ethical principles, life expectancy, anxiety, depression, and stress is positive and significant. The higher the panic from COVID-19, the more ethical principles, life expectancy, anxiety, depression, and stress. Since no study has been carried out so far on the effect of prevention and panic from COVID-19, ethical principles, life expectancy, depression, and stress in Iraqi firms, the present study results can provide valuable information and contribute to the development of science and knowledge.

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“…They have to be constrained to as Small a variety as feasible of promising drugs. Acknowledging the staggering Translational procedure that resulted in the improvement of multiple Vaccine products, the search for COVID 19 treatments has Been fraught with hyperbolic claims, miscommunication of lookup findings, poorly designed and underpowered clinical studies, science-by-press release and business Efforts to take advantage of for income the public"s fears and anxietie 3 . Several coronavirus disease 2019 (COVID- 19) vaccines are currently in human trials.…”

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2022

IJPSR

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The novel coronavirus disorder 2019 (COVID-19) outbreak commenced in early December 2019 in the capital metropolis of Wuhan, Hubei province, People"s Republic of China and precipitated a world pandemic on march 11, 2020. Though some the international locations have succeeded in slowing down the price of the unfold of this pandemic, most the international locations throughout the globe are nevertheless persevering with To journey and growing vogue in the increase and unfold of this lethal disease. Hence, in the present day scenario, it has grown to be necessary to manipulate and eventually irradicate this lethal sickness using a nice vaccine. An RNA-based vaccine would possibly be greater superb than ordinary as vaccines to deal with a pandemic treatment. However, administration of acute seizures in sufferers with COVID19 as properly as administration of PWE and COVID19 wishes to think about doable drug-drug interactions between antiseizure capsules and candidate tablets presently assessed as therapeutic preferences for COVID-19. In this paper, we look at moral troubles and public conversation challenges associated with the improvement of cell-based therapeutics for COVID19. INTRODUCTION:Since the first described contamination with extreme acute respiratory Syndrome coronavirus two (SARS-CoV-in December 2019, Coronavirus sickness 2019 (COVID-19) has developed into a Pandemic, the signs of which vary from asymptomatic course to pneumonia, acute lung and/or multiorgan failure and Death 1 . This virus has a greater diploma of lethality than different endemic viruses. It is also greater deadly to humans in contrast to the previously rising outbreaks of SARS-CoV-1 in 2003 and Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012 4 . Currently, there are no therapeutics accepted with the aid of the US Food and Drug Administration (FDA) for the therapy of COVID-19 7 .

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Ethical issues and public communication in the development of cell-based treatments for COVID-19: Lessons from the pandemic

Cited by 12 publications

References 32 publications

Education for the translation of Advanced Therapy Medicinal Products

Education for the translation of Advanced Therapy Medicinal Products

The Relationship between Prevention and Panic from COVID-19, Ethical Principles, Life Expectancy, Anxiety, Depression and Stress

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