Ethical Review Issues in Collaborative Research Between Us and Low – Middle Income Country Partners: A Case Example

McIntosh, Scott; Sierra, Essie; Dozier, Ann; Díaz, Sergio; Quiñones, Zahíra; Primack, Aron; Chadwick, Gary L.; Ossip-Klein, Deborah J.

doi:10.1111/j.1467-8519.2008.00662.x

Cited by 21 publications

(19 citation statements)

References 14 publications

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“…We continue to report findings from PDT studies elsewhere (e.g., Chin, et al in press; Dozier et al, 2006, 2009, 2014; Lando et al 2010; McIntosh, et al, 2008; Ossip-Klein, et al 2008; Ossip, et al; 2013, 2015; Prucha, et al 2015; Torres, et al 2011, 2014; Wipfli, et al 2008). The current paper will report on lessons learned from implementing this US-DR partnered research.…”

Section: Research Rationale/descriptionmentioning

confidence: 87%

“…We have described IRB complexities for US-LMIC research elsewhere (McIntosh et al, 2008), and will note key lessons learned here. First, especially for teams without prior experience with their IRBs for global research, it is valuable to have face to face meetings with IRB representatives to review study protocols, clarify proper steps, and problem solve challenging issues.…”

Section: Establishing An Infrastructure For Tobacco Cessation Researcmentioning

confidence: 99%

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Lessons Learned from Twelve Years of Partnered Tobacco Cessation Research in the Dominican Republic

et al. 2016

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Engaging partners for tobacco control within low and middle income countries (LMICs) at early stages of tobacco control presents both challenges and opportunities in the global effort to avert the one billion premature tobacco caused deaths projected for this century. The Dominican Republic (DR) is one such early stage country. The current paper reports on lessons learned from 12 years of partnered United States (US)-DR tobacco cessation research conducted through two NIH trials (Proyecto Doble T, PDT1 and 2). The projects began with a grassroots approach of working with interested communities to develop and test interventions for cessation and secondhand smoke reduction that could benefit the communities, while concurrently building local capacity and providing resources, data, and models of implementation that could be used to ripple upward to expand partnerships and tobacco intervention efforts nationally. Lessons learned are discussed in four key areas: partnering for research, logistical issues in setting up the research project, disseminating and national networking, and mentoring. Effectively addressing the global tobacco epidemic will require sustained focus on supporting LMIC infrastructures for tobacco control, drawing on lessons learned across partnered trials such as those reported here, to provide feasible and innovative approaches for addressing this modifiable public health crisis.

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Section: Research Rationale/descriptionmentioning

confidence: 87%

Section: Establishing An Infrastructure For Tobacco Cessation Researcmentioning

confidence: 99%

Lessons Learned from Twelve Years of Partnered Tobacco Cessation Research in the Dominican Republic

et al. 2016

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“…Committees are not independent enough, according to the history of their creation and the socio-economic context; Gov/MRC, the Gambia ethics committee, is the best example of dependence. In addition, ethics committees in developing countries are required to adhere to standards that might impose practices that conflict with local culture and interpretations of ethics 25. African countries should introduce a framework for research governance based on international guidelines and local cultural, medical and legal realities.…”

Section: Discussionmentioning

confidence: 99%

Ethics committees for biomedical research in some African emerging countries: which establishment for which independence? A comparison with the USA and Canada

Rwabihama

Girre

2010

J Med Ethics

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“…Three were tobacco-producing. The four remote communities had participated in our prior trial (Ossip-Klein, et al, 2008; Dozier, et al, 2006, 2009, 2014; McIntosh, et al, 2008; Torres, et al, 2013). …”

Section: Methodsmentioning

confidence: 99%

Tobacco Cessation in Economically Disadvantaged Dominican Republic Communities: Who are the Ex-Users?

et al. 2015

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Introduction Tobacco use and harm continue to increase in low- and middle income countries (LMICs) globally. Smoking cessation is the most effective means of reducing morbidity and mortality from tobacco use. Increasing the prevalence of ex-users is an indicator of population cessation. Aims This study provides the first examination of factors associated with ex-tobacco use status in the Dominican Republic (DR), a LMIC in the Latin America and Caribbean region. Methods Baseline surveillance was conducted for 1177 randomly selected households in 7 economically disadvantaged DR communities (total N=2680 adult household members). Results Ex-user prevalence was 10.6% (1.0%–18.5% across communities), 14.8% were current users (9.1–20.4), and quit ratios were 41.7% (9.7%–52.7%). Among ever-users, females (OR 2.02, 95% CI 1.41, 2.90), older adults (45–64: OR 1.75, 95% CI 1.12, 2.74; 65+: OR 2.09, 95% CI 1.29, 3.39), and those who could read/write (OR 1.64, 95% CI 1.08, 2.50), had health conditions (OR 1.63, 95% CI 1.11, 2.41), and lived with ex-users (OR 1.70, 95% CI 1.12, 2.58) were over 60% to two times as likely to be ex-users. Those from remote communities (OR 0.52, 95% CI 0.36, 0.74), using chewed tobacco (OR 0.14, 95% CI 0.04, 0.48) and living with tobacco users (OR 0.55, 95% CI 0.37, 0.81) were less likely to be ex-users. Conclusions Ex-user prevalence and quit ratios were lower than for high income countries. Implementing broad tobacco control measures, combined with clinically targeting vulnerable groups, may increase tobacco cessation to most effectively reduce this public health crisis.

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Ethical Review Issues in Collaborative Research Between Us and Low – Middle Income Country Partners: A Case Example

Cited by 21 publications

References 14 publications

Lessons Learned from Twelve Years of Partnered Tobacco Cessation Research in the Dominican Republic

Lessons Learned from Twelve Years of Partnered Tobacco Cessation Research in the Dominican Republic

Ethics committees for biomedical research in some African emerging countries: which establishment for which independence? A comparison with the USA and Canada

Tobacco Cessation in Economically Disadvantaged Dominican Republic Communities: Who are the Ex-Users?

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