Unethical pro-organizational behavior (UPB) has received growing attention from organizational scholars in recent years. As leadership is a key predictor of employee behavior in organizations, research focusing on leadership and UPB holds great potential for theoretical and practical advancements. The current paper presents a comprehensive systematic review of published research exploring leadership and UPB since 2010. The review not only situates the concept of UPB within the relevant literature, but also incorporates various analyses, including context, theoretical perspective, and research design. It also identifies the leadership-based independent variables, mediators, and moderators that impact UPB, which can help advance future theorizing in the field. Lastly, the paper offers suggestions for future research that can help in repositioning the field in order to build more reliable and valuable theoretical and practical policy recommendations.