Ethics Priorities of the Curing Coma Campaign: An Empirical Survey

Lewis, Ariane; Claassen, Jan; Illes, Judy; Jox, Ralf J.; Kirschen, Matthew; Rohaut, Benjamin; Trevick, Stephen; Young, Michael J.; Fins, Joseph J.

doi:10.1007/s12028-022-01506-2

Cited by 11 publications

(1 citation statement)

References 27 publications

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“…Future studies should be mindful of ethical considerations related to DoC research. 6,7 Outcome metrics should account for neurocognitive, social, and emotional development that would have occurred in the absence of brain injury and consider a child's baseline neurologic capabilities. Studies should include metrics to evaluate the impact of access to neurocritical care and rehabilitation services including issues related to diversity and equity.…”

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confidence: 99%

Beyond Coma Scales

Kirschen

King

2023

Neurology

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Children who experience an acute brain injury are often comatose, either from direct insult to the brain's centers that control awareness and arousal or because of receiving CNS depressing medications or both. Whether a child will emerge from their comatose state depends on numerous factors including the etiology and severity of their brain injury, age, comorbid medical conditions, and the impact of neuroprotective therapies. Disorders of consciousness (DoC) are clinical states classified based on the degree of wakefulness, awareness of oneself or their environment, and signs of consciousness and communication. Vegetative state/ unresponsive wakefulness syndrome (VS/UWS) and minimally conscious state (MCS) are DoC that children may manifest as they recover from their acute brain injury. Accurately identifying a child's DoC has implications for neuroprognostication and guiding neurorestorative therapies.

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confidence: 99%