Ethnic Variation in Central Corneal Refractive Power and Steep Cornea in Asians

Pan, Chen-Wei; Cheng, Ching‐Yu; Sabanayagam, Charumathi; Chew, Merwyn; Lam, Janice; Ang, Marcus; Wong, Tien Yin

doi:10.3109/09286586.2014.887735

Cited by 33 publications

(41 citation statements)

References 26 publications

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“…In addition, the different prevalence in geographic regions could be explained by ethnic differences rather than amount of sunshine. In fact, ethnic differences have been noted in people inhabiting the same geographic location: In the English Midlands, Asian (Indian, Pakistani and Bangladeshi) patients have been found to be 4.4 and 7.5 times more likely to have KC than Caucasians, Maori in New Zealand have been reported to have a higher prevalence of KC than other people in the same country, non‐Persians (Arabs, Kurds, Turks) living in the same city in Iran have been found to have KC prevalence of 7.9% compared to 2.5% in a Persian ethnic group and Indians have been found to have significantly steeper corneas than Chinese and Malays all living in Singapore . It is worth noting that in each of the aforementioned studies the diagnostic criteria and age groups were controlled.…”

Section: Discussionmentioning

confidence: 99%

Risk factors for keratoconus in Israel: a case–control study

Gordon‐Shaag

Millodot

Kaiserman³

et al. 2015

Ophthalmic Physiologic Optic

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Section: Discussionmentioning

confidence: 99%

Risk factors for keratoconus in Israel: a case–control study

Gordon‐Shaag

Millodot

Kaiserman³

et al. 2015

Ophthalmic Physiologic Optic

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“…Hashemi et al [11] further reported that in Iran, non-Persian populations (Arabs, Turks and Kurds) had three times the prevalence than Persian ethnic populations. According to Pan et al [18], steeper corneas were found in Indians compared to Malays or Chinese in Singapore.…”

Section: Epidemiology and Prevalencementioning

confidence: 99%

Pediatric keratoconus: a review of the literature

2017

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Purpose To describe the epidemiology and prevalence, rates of progression, difference between adult and pediatric populations, and therapeutic approaches to pediatric keratoconus from documented literature. Methods A literature search was done on PubMed using key words including pediatric keratoconus, children with keratoconus, adult keratoconus, penetrating keratoplasty, corneal cross-linking and intra-corneal ring segments. The literature was reviewed and reported to explore the key epidemiological differences between the pediatric and adult population with regards to presentation and treatment options. Results Pediatric keratoconus is more aggressive than adult keratoconus, which has been explained by structural differences in the cornea between both populations. High rates of progression were documented in pediatric populations. While corneal collagen cross-linking, intracorneal ring segments and penetrating keratoplasties have been used as therapies in the pediatric population, the literature overwhelmingly shows higher rates of failure and progression despite these measures as compared to adults. Conclusion Pediatric keratoconus is more aggressive than adult keratoconus, and current therapies used in adults may not be sufficient for the pediatric population.

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“…10 and in a comparison of the three major ethnic groups of Singapore (Chinese, Malays and Indians), Indians had significantly steeper corneas than the other groups. 23 Endogamy and/or consanguinity would appear to play a major role in these communities, as was shown in a recent study. 24 However, ethnic differences do not appear to prevail universally since similar KC prevalence was observed in India 7 and China.…”

Section: Introductionmentioning

confidence: 59%

Prevalence of Keratoconus among Young Arab students in Israel

Barbara¹,

Gordon‐Shaag²,

Millodot³

et al. 2014

International Journal of Keratoconus and Ectatic Corneal Diseases

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Purpose:To determine the prevalence of keratoconus (KC) in an Arab population in Israel. Materials and methods:Videokeratography was performed on volunteer students from the Academic Arab College of Education, in Haifa, Israel. All participants filled out a self-administered questionnaire to evaluate possible risk factors for KC. Univariate and multivariate analysis were performed.Results: Data of 314 participants were analyzed and a prevalence of (N = 10), 3.18% (95% CI, 1.2 to 5.1%) was found. The only significant factor (both in univariate and multivariate analysis) that was associated with KC was parental consanguinity (OR 5.10, p = 0.02). Druzes and Bedouins had a higher prevalence than Muslims and Christians. However, the differences were not significant possibly due to the small size of the sample. Conclusion:The result of this study was similar to other studies conducted in the Middle East, which indicate a higher prevalence of KC than in western countries. It is also recommended that people who have consanguinity in their family should be topographically tested to detect the early stages of KC.

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Ethnic Variation in Central Corneal Refractive Power and Steep Cornea in Asians

Cited by 33 publications

References 26 publications

Risk factors for keratoconus in Israel: a case–control study

Risk factors for keratoconus in Israel: a case–control study

Pediatric keratoconus: a review of the literature

Prevalence of Keratoconus among Young Arab students in Israel

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