Ethno-medicinal plants used by local folk healers ‘<i>Vaidyas’</i> in tribal dominated districts of Jharkhand

Rathi, R. S.; Bhatt, KC; Semwal, DP; Ahlawat, Sandeep; Tomar, J. B.

doi:10.5958/0975-6892.2019.00003.0

Cited by 2 publications

(1 citation statement)

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“…Some of its Ayurvedic usages include its use as antineoplastic, antitussive, antihepatotoxic, galactagogue, and aphrodisiac agent [3][4][5][6][7]. In India, the use of this plant against intestinal helminths has been documented in the states of Jharkhand, Kashmir and Assam [8][9][10].…”

Section: Introductionmentioning

confidence: 99%

Studies on the anthelmintic potentials of the roots of Asparagus racemosus willd. (Asparagaceae)

Soren

Yadav

2021

Clin Phytosci

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Background The Santhal tribe in Assam, India use the roots of Asparagus racemosus (Asparagaceae) as a deworming remedy. The study aimed to investigate the anthelmintic credentials of this plant, using two representative groups of helminth parasites. Methods The in vitro testing was conducted against Hymenolepis diminuta (cestode) and Syphacia obvelata (nematode). Parasites were exposed to 10, 20 and 30 mg/ml concentrations of plant extract, and efficacy was adjudged on the basis of parasites paralysis and mortality. In vivo efficacy was examined using H. diminuta-rat and S. obvelata-mice models where animals were administered 125, 250 and 500 mg/kg doses of extract. Results In vitro assay, against H. diminuta revealed that at 30 mg/ml concentration the extract showed almost a comparable efficacy with that of reference drug praziquantel (PZQ) (1 mg/ml). The in vitro efficacy of extract against S. obvelata was however lower than H. diminuta. In vivo studies against H. diminuta at 500 mg/kg revealed 53.88 and 24 % reduction in eggs per gram (EPG) and worm counts respectively. Against S. obvelata the extract showed 26.61 and 30.93 % reduction for the same. Conclusions The findings of this study present suggest that the roots of A. racemosus are effective against intestinal helminthic infections and justifies its use as an anthelmintic in the traditional medicine of the Santhals.

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