Ethnobotany studies human‒plant interactions, focusing on plant use for treating and preventing illnesses in humans and animals. It delves into indigenous knowledge, cultural practices, and religious rituals related to medicinal plants. Historical evidence from Egypt, Babylon, India, and China highlights the extensive use of plant-based remedies. For example, the Ebers Papyrus and Ayurvedic texts detail ancient treatments. The Amazon rainforest provides plants such as Andiroba and Copaifera for skincare, whereas Chinese medicine uses herbs such as Chinese knotweed and star anise. Ancient Egyptians employed plants such as marshmallows and pomegranates. Ayurveda in India utilizes neem and turmeric, and Nigeria's flora includes garlic and bitter orange for traditional skincare. This highlights the crucial role of plants across cultures, reflecting a rich heritage of ethnobotanical knowledge informing modern practices.