Ethnobotanical study of indigenous nutri-medicinal plants used for the management of HIV/AIDS opportunistic ailments among the local communities of central Uganda

Nakibuuka, Mary Magdalein; Mugabi, Robert

doi:10.1016/j.sciaf.2022.e01245

Cited by 2 publications

(1 citation statement)

References 25 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…For instance, “α-Zam” has been shown to significantly increase CD4 counts by an average of 454 cells/uL and reduce viral load (HIV-RNA) from an average of 423,000 copies/mL to undetectable levels (≤50 copies/mL). These improvements resulted in the absence of HIV-related symptoms, indicating potent anti-HIV effects in herbal mixtures like “α-Zam.” These findings align with previous studies demonstrating the preventive efficacy of some herbal medicines against HIV infection ( 32 ).…”

Section: Potential Herbal Approachessupporting

confidence: 93%

HIV/AIDS in Indonesia: current treatment landscape, future therapeutic horizons, and herbal approaches

Jocelyn,

Nasution,

Nasution

et al. 2024

Front. Public Health

View full text Add to dashboard Cite

HIV/AIDS is still a major worldwide health concern, and Indonesia is making efforts to mitigate its effects. Antiretroviral therapy (ARV), which aims to decrease viral replication, boost immunological function, and lengthen the lifespans of persons living with HIV/AIDS, is the cornerstone of Indonesia’s strategy. The availability of ARV has significantly increased, yet problems including stigma and the requirement for regular medication adherence still exist. To address the broader needs of those affected by HIV/AIDS, Indonesia lays a major focus on comprehensive care, which includes mental health and social support, in addition to ARV. Data show that, despite progress, there is still a stigma surrounding HIV/AIDS, which affects patient outcomes and access to care. With vigorous research into cutting-edge antiretroviral medications and treatment techniques, Indonesia has a thriving future therapeutic landscape. The goals of these programs are to increase treatment effectiveness, decrease side effects, and increase access to cutting-edge treatments. Preventive methods, such as PrEP (pre-exposure prophylaxis), are making progress, and efforts to find a cure are gaining prominence. Notably, HIV/AIDS management plan of Indonesia heavily relies on natural remedies. Patient care incorporates traditional Indonesian medicine, such as jamu and several herbal medicines. Although there is little scientific proof to support the effectiveness of these herbal remedies, complementary and alternative therapies frequently employ them to manage symptoms and promote general wellness. In terms of the 95-95-95 targets, Indonesia is making an effort to comply with these international goals by seeking to diagnose 95% of HIV-positive individuals, provide sustained ARV to 95% of those diagnosed, and achieve viral suppression in 95% of ARV recipients. Although there are gaps in reaching these aims, progress is being made, in part because of the aforementioned challenges. In summary, Indonesia employs a multimodal approach to HIV/AIDS management, including traditional herbal cures, continuous research into cutting-edge treatments, and conventional ARV. In order to enhance overall health outcomes and create a healthier society, the future of HIV/AIDS treatment in Indonesia is concentrated on expanding therapeutic alternatives, reaching the 95-95-95 targets, decreasing stigma, and improving access to care.

show abstract

Section: Potential Herbal Approachessupporting

confidence: 93%

HIV/AIDS in Indonesia: current treatment landscape, future therapeutic horizons, and herbal approaches

Jocelyn,

Nasution,

Nasution

et al. 2024

Front. Public Health

View full text Add to dashboard Cite

show abstract

Qualitative Phytochemical Screening of Medicinal Plants Using Different Solvent Extracts

et al. 2023

View full text Add to dashboard Cite

Medicinal plants are rich in bioactive components that are utilized to treat various human ailments. They are crucial to healing as well. Phytochemical constituents are responsible for the medicinal activity of plant species. Phytochemical screening is an important step in identifying bioactive compounds present in particular medicinal plants. Hence, in this present work, phytochemical screening of leaf extract of some traditional medicinal plants, namely Cannabis sativa, Ricinus communis, and Bryophyllum pinnatum was carried out. The solvent extracts of the leaves of respective plants were prepared using the Soxhlet apparatus with acetone, chloroform, petroleum ether, and aqueous solvents. Qualitative phytochemical analysis of plants included tests for reducing sugars, flavonoids, steroids, glycosides, polyphenols, tannins, terpenoids, and coumarins. All eight tested phytoconstituents were found present in all three plants in any solvent extracts. Aqueous extract confirmed the presence of a maximum number of phytoconstituents in C. sativa in comparison to other solvents. Acetone confirmed the maximum and chloroform confirmed the minimum number of phytoconstituents in R. communis, while chloroform confirmed the maximum and aqueous extract confirmed the minimum number of phytoconstituents in B. pinnatum. These phytochemicals may be a source of innovative plant-based medications because their existence is connected with the therapeutic potential of these plants.

show abstract

Ethnobotanical study of indigenous nutri-medicinal plants used for the management of HIV/AIDS opportunistic ailments among the local communities of central Uganda

Cited by 2 publications

References 25 publications

HIV/AIDS in Indonesia: current treatment landscape, future therapeutic horizons, and herbal approaches

HIV/AIDS in Indonesia: current treatment landscape, future therapeutic horizons, and herbal approaches

Qualitative Phytochemical Screening of Medicinal Plants Using Different Solvent Extracts

Contact Info

Product

Resources

About