Ethnobotanical Study of Medicinal Plants of Kashmir Valley, India Having Anticancer Properties

Abstract

Kashmir valley is inhabited by various tribes living in close vicinity of enriched forests. These tribes have always used medicinal plants for the treatment of various diseases by traditional methods. Utilization of medicinal plants is directly linked to their culture and history. There are many tribes and villages that are repositories of indigenous knowledge and practice. With due attention to rapid progress in the phytochemical study of plants, they are becoming popular because of their anticancer effects. Documentation of such knowledge is required in view of day to day disappearing knowledge in the new generations. Therefore, in the present study an attempt has been made to document some locally available plants utilized traditionally by the inhabitants of the valley and are having anticancer properties. These plants are likely to provide effective anticancer agents. The aim of this study is to investigate the effective medicinal plants in the treatment of cancer and study their mechanism of action.

Integrated study of HR-LC/MS and network pharmacology to identify breast cancer-related molecular targets of Fritillaria cirrhosa D. Don active constituents in combination with molecular dynamic simulation and experimental evaluation

“…It is necessary to develop e cient treatments to prevent, delay, or reverse the occurrence of breast cancer in high-risk women. Natural products are better at chemoprevention of breast cancer than synthetic ones because they have fewer adverse effects and lower toxicity 15 . Natural product research has attracted a lot of attention recently for the treatment of breast cancer.…”

“…Furthermore, approximately 60% of anticancer drugs are derived from the plant kingdom 14,17 . Numerous essential modern drugs, including digitoxin, reserpine, tubocurarine, ephedrine, ergometrine, atropine, and aspirin, were found by tracing their roots to their traditional uses 15 . For example, vinblastine and vincristine, which are used to treat pediatric leukemia and Hodgkin's disease, are produced from Catharanthus roseus, an African periwinkle.…”

“…Several research studies have revealed that about 25-28% of all current medications are believed to be obtained directly or indirectly from higher plants, indicating the immense potential of plants that have been exploited for ages [14][15][16] . Furthermore, approximately 60% of anticancer drugs are derived from the plant kingdom 14,17 .…”