Ethnobotanical survey of medicinal plant Mentha rotundifolia (L.) Huds. in El Tarf, extreme northeast of Algeria.

Djekoun, Meriem; Boughendjioua, Hicham; Khelfaoui, Mohamed; Boubekeur, Mohamed; Djekoun, Manel; Rekioua, Naouel; Benaliouche, Fouzia; Saidi, Nour; Riadi, Fadhila

doi:10.5455/jcmr.2022.13.01.04

Cited by 2 publications

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Hepatoprotective activity of Mentha rotundifolia aqueous extract against hepatocellular damage induced by CCL ₄ in rats

Ferdjioui,

Belhattab,

Ouhida

et al. 2024

Natural Product Research

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This study aims to assess hepatoprotective properties of of M. rotundifolia. Decoction was used to prepare the aqueous extract. The preliminary cytotoxicity evaluated against Caco 2 and RAW 264 cells demonstrate no cytotoxic effect. The preventive impact of the extract against liver damage was evaluated by examining blood levels of AST, ALT, ALP, total proteins, and histological alterations in liver tissues. Thirty albino rats were separated into five groups: the first served as normal group, the second was injected by olive oil (3ml/kg), and the third was injected by CCL 4 (3ml/kg). However, groups IV and V received daily doses of 250 and 500 mg extract/kg bw, respectively before CCL 4 injection. The results showed that the administration of the extract led to a marked improvement in plasma biochemical markers and a reduction in symptoms of CCL4-induced liver damage. The extract exhibits hepatoprotective activity, which may be attributed to its phytochemical components.

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Hepatoprotective activity of Mentha rotundifolia aqueous extract against hepatocellular damage induced by CCL ₄ in rats

Ferdjioui,

Belhattab,

Ouhida

et al. 2024

Natural Product Research

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The Genus Mentha L.

Olcay

2024

Medicinal Spices

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Mentha, a genus of plants known throughout history for its use as a spice by humans, has been documented since ancient times. This famous plant has been used both as a spice and for its medicinal properties in the treatment of many ailments. Mentha spp have anti-inflammatory, antioxidant, antinociceptive, hepatoprotective, antibacterial and antifungal activities. Pharmacological evidence supports the biological activities of these species, which are widely used in traditional medicine.

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Ethnobotanical survey of medicinal plant Mentha rotundifolia (L.) Huds. in El Tarf, extreme northeast of Algeria.

Cited by 2 publications

References 0 publications

Hepatoprotective activity of Mentha rotundifolia aqueous extract against hepatocellular damage induced by CCL ₄ in rats

Hepatoprotective activity of Mentha rotundifolia aqueous extract against hepatocellular damage induced by CCL ₄ in rats

The Genus Mentha L.

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Ethnobotanical survey of medicinal plant Mentha rotundifolia (L.) Huds. in El Tarf, extreme northeast of Algeria.

Cited by 2 publications

References 0 publications

Hepatoprotective activity of Mentha rotundifolia aqueous extract against hepatocellular damage induced by CCL 4 in rats

Hepatoprotective activity of Mentha rotundifolia aqueous extract against hepatocellular damage induced by CCL 4 in rats

The Genus Mentha L.

Contact Info

Product

Resources

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Hepatoprotective activity of Mentha rotundifolia aqueous extract against hepatocellular damage induced by CCL ₄ in rats

Hepatoprotective activity of Mentha rotundifolia aqueous extract against hepatocellular damage induced by CCL ₄ in rats